Results 41 to 50 of about 221,099 (246)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Spelling out of scope taking arguments in (de-)verbal constructions in Hungarian

LingBaW, 2022
The paper systematically investigates operators in post-head positions within the three constructions referring to states of affairs in Hungarian, that is, within verbal, deverbal nominal and infinitival phrases. Hungarian is well-known to be a language
Judit Farkas, Gábor Alberti
doaj   +1 more source

Operators Approximable by Hypercyclic Operators [PDF]

Mathematical Proceedings of the Royal Irish Academy, 2015
We show that operators on a separable infinite dimensional Banach space $X$ of the form $I +S$, where $S$ is an operator with dense generalised kernel, must lie in the norm closure of the hypercyclic operators on $X$, in fact in the closure of the mixing operators.
openaire   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Operators Commuting with Positive Operators [PDF]

Proceedings of the American Mathematical Society, 1979
Necessary and sufficient conditions are obtained for an operator to commute with a positive operator.
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Power vector inequalities for operator pairs in Hilbert spaces and their applications

Open Mathematics
This study explores the power vector inequalities for a pair of operators (B,C)\left(B,C) in a Hilbert space. By utilizing a Mitrinović-Pečarić-Fink-type inequality for inner products and norms, we derive various power vector inequalities.
Altwaijry Najla, Dragomir Silvestru Sever, Feki Kais   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

New Novel and Mathematic [PDF]

Slovenska Literatura, 2007
Author in the study damasks false analogy of a genre of new novel with mathematic creating process as it was proposed by some theoreticians. New novel according to theoretical assumptions of the representatives of the theory replaces a function of ...
Stanislaw Lem
doaj