Results 91 to 100 of about 47,007 (284)
CKAP4 Regulates ERS‐Induced Apoptosis in Osteoclasts Through FOXO3 in Periodontitis
CKAP4 promotes the transcription of PERK via FOXO3 in OCs, thereby facilitating ER stress‐induced apoptosis. In periodontitis, the reduction of CKAP4 in OCs leads to decreased OC apoptosis, which exacerbates alveolar bone resorption. ABSTRACT Periodontitis is a prevalent oral disease characterised by chronic inflammation and irreversible alveolar bone ...
Jiayu Cheng +12 more
wiley +1 more source
Immunohistochemical localization of RANK, RANKL and OPG in healthy and arthritic canine elbow joints
OBJECTIVE: To determine if the receptor activator of nuclear factor-kappaB-receptor activator of nuclear factor-kappaB ligand-osteoprotegerin (RANK-RANKL-OPG) system is active in bone remodeling in dogs and, if so, whether differences in expression of ...
DIETER D. BOSSHARDT +17 more
core +1 more source
ABSTRACT Introduction Clinical reasoning is considered a core skill for physicians, and its training should already be addressed in undergraduate medical education. At the University Medical Center Göttingen, students have been able to engage in formative key feature examinations since 2013.
Marc André Ackermann +4 more
wiley +1 more source
A Starting from the initial conditions described in Figure 3, the RANKL and OPG concentrations, the osteoclast population density (OC) and the tumor density (Tumor) are shown after 30, 60 and 90 days, respectively. The growing tumor produces OPG at rates
Marc D. Ryser (125274) +2 more
core +1 more source
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that predominantly affects small joints, causing persistent pain, functional impairment, and a marked reduction in patients’ quality of life.
Yu. V. Chumacheva +4 more
doaj +1 more source
Cyclic β‐1,2‐glucan (CβG)‐associated solute‐binding protein of type I ABC transporter was originally identified in Chloroflexus aurantiacus, a phototrophic bacterium. Crystal structures in complex with CβGs revealed unique binding modes that are fundamentally distinct from that of the short β‐1,2‐glucooligosaccharides‐binding protein.
Kazuya Kato +6 more
wiley +1 more source
OBJECTIVE: To evaluate and compare the expression levels of Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) and Osteoprotegerin (OPG) in canine periodontal tissues subjected to periodontal distraction versus conventional retraction at ...
Osama Eissa +5 more
doaj +1 more source
ABSTRACT Objectives To describe the prevalence, extent and severity of periodontitis in an adult Norwegian population, using the 2017 EFP/AAP and CDC/AAP case definitions, and their associations with potential risk factors for periodontitis. A secondary aim was to explore how the stage and grade of periodontitis shifted when complexity and risk factors
Gro Eirin Holde +2 more
wiley +1 more source
ABSTRACT Background Hypercementosis is a non‐neoplastic condition characterized by excessive cementum deposition along the root surface, resulting in altered apical morphology. Although often asymptomatic and detected incidentally on radiographs, changes in apical contour may influence anatomical complexity in endodontic treatment.
Carlos Segura‐Raya +3 more
wiley +1 more source

