Results 91 to 100 of about 77,539 (257)
Neurobiology of Disease, 2013 Osteoprotegerin (OPG) is a key regulator of bone remodeling. Mutations and variations in the OPG gene cause many human diseases that are characterized by not only skeletal abnormalities but also poorly understood hearing loss: Paget's disease ...
Shyan-Yuan Kao +6 more
doaj +1 more source
Trajectory-Based Off-Policy Deep Reinforcement Learning
, 2019 Policy gradient methods are powerful reinforcement learning algorithms and have been demonstrated to solve many complex tasks. However, these methods are also data-inefficient, afflicted with high variance gradient estimates, and frequently get stuck in ...
Daniel, Christian +4 more
core
Learning gradients on manifolds
, 2010 A common belief in high-dimensional data analysis is that data are concentrated on a low-dimensional manifold. This motivates simultaneous dimension reduction and regression on manifolds.
Mukherjee, Sayan +2 more
core +1 more source
Minireview: The OPG/RANKL/RANK System [PDF]
Endocrinology, 2001 The identification of the OPG/RANKL/RANK system as the dominant, final mediator of osteoclastogenesis represents a major advance in bone biology. It ended a long-standing search for the specific factor produced by preosteoblastic/stromal cells that was both necessary and sufficient for osteoclast development. The initial cloning and characterization of
openaire +2 more sources
Journal of Periodontology, EarlyView.Abstract Background Sodium alendronate (ALN) is widely used to treat postmenopausal osteoporosis, but both estrogen deficiency and antiresorptive therapy may impair alveolar bone repair after tooth extraction. A clinically relevant but insufficiently explored scenario involves estrogen‐deficient individuals receiving hormone replacement therapy (HRT ...
Pedro H. C. Isaias +9 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley +1 more source
Эндодонтия Today, 2020 Modern techniques of medical visualisation are a base of additional diagnostic and planning methods of surgical treatment in stomatology and maxillofacial surgery.
doaj
Frontiers of Bright CEP‐Stable Broadband Infrared Sources
Laser &Photonics Reviews, EarlyView.Bright CEP‐stable broadband infrared sources push the limits of ultrafast science by delivering exceptional brightness alongside few‐cycle durations and multi‐octave spectral coverage. This review highlights emerging architectures and nonlinear conversion strategies that scale power while preserving phase stability.
Ugaitz Elu, Jens Biegert
wiley +1 more source
Bone & Joint ResearchAims: The present study investigated receptor activator of nuclear factor kappa-Β ligand (RANKL), osteoprotegerin (OPG), and Runt-related transcription factor 2 (RUNX2) gene expressions in giant cell tumour of bone (GCTB) patients in relationship with ...
Raja Amri +6 more
doaj +1 more source
Wildlife Letters, EarlyView.Eimeria saudiensis represents a genus of apicomplexan parasites capable of inducing coccidiosis in Arabian oryx. Our research concentrated on the morphological and molecular investigation of Eimeria spp. in the captive oryx herd in Oman. The therapeutic and management practices employed at the Mammals Breeding Center were reassessed to diminish ...
Khalid Al‐Habsi +7 more
wiley +1 more source