Results 101 to 110 of about 35,866 (219)

Long‐term stability of horizontal bone augmentation at implant sites

Periodontology 2000, EarlyView.
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu, Hui Jia Sophia Choo, Ding‐Sen Ong, Henry Kwek   +3 more
wiley   +1 more source

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

Bone biology in aging periodontal and peri‐implant tissues

Periodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa, Giuseppe Intini, Daniel Clark   +2 more
wiley   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Effect of Adeno-Associated Virus-Transfected Mesenchymal Stem Cells Containing Agents on Bone Formation in Extended Inter-Premaxillary Suture in Rats

Journal of Craniomaxillofacial Research
Introduction: The aim of this study was to investigate the histomorphometric effects of bone marrow-derived mesenchymal stem cells (MSCs) transfected with Adeno Associated Virus (AAV) and containing bone morphogenic protein 7 (Bmp7) or osteoprotegerin ...
Feyza Eraydın, Alev Cumbul, Merve Kurnaz, Fulya Ozdemir   +3 more
doaj  

RET-driven osteoprotegerin expression links medullary thyroid cancer to osteoblastic bone metastases. [PDF]

Cell Rep Med
Bagheri-Yarmand R, Pagnotti GM, Kidd JL, Ramirez DA, Trupti Trivedi, Guerra L, Wang Z, Cruz LM, Moehle JM, Jebaraj YS, Wan X, Song JH, Bassett RL, Lin SH, Hu MI, Sherman SI, Hofmann MC, Guise TA.   +17 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

A dual-action humanized DKK-1 antibody that activates the Wnt/β-catenin signaling pathway and inhibits the RANKL signaling pathway for osteoporosis therapy. [PDF]

Front Immunol
Hou S, Gao T, Wu Y, Wang H, Zhang D, Guo Q, Xu J, Guo H, Qian W.   +8 more
europepmc   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Comparative evaluation of RANKL and OPG levels in gingival crevicular fluid and saliva during orthodontic treatment using thermoformed and direct-printed aligners. [PDF]

Dental Press J Orthod
Lakshmanan P, Baskaran S, Alamelu S, Baskar K.   +3 more
europepmc   +1 more source