Results 91 to 100 of about 36,524 (294)

Release of Ciprofloxacin and Moxifloxacin From Daily Disposable Contact Lenses From an In Vitro Eye Model [PDF]

, 2015
Bajgrowicz, M., Phan, C.-M., Subbaraman, L. N., & Jones, L. (2015). Release of Ciprofloxacin and Moxifloxacin From Daily Disposable Contact Lenses From an In Vitro Eye Model. Investigative Opthalmology & Visual Science, 56(4), 2234.
Bajgrowicz-Cieslak, Magdalena, Jones, Lyndon W., Phan, Chau-Minh, Subbaraman, Lakshman N.   +3 more
core   +1 more source

Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis

Animal Models and Experimental Medicine, EarlyView.
This study developed a biosafe, accessible, and versatile murine model of bone TB using Mycobacterium smegmatis, a fast‐growing, nonpathogenic mycobacterial species with high genomic homology to Mycobacterium tuberculosis. Three infection routes—subperiosteal calvarial injection, intratibial injection, and intracardiac (left ventricular) inoculation ...
Yewei Jia, Yuhuai Guo, Yusheng Yang, Jie Zhang, Ziyang Zhang, Ying Qu, Jiulin Tan, Jie Shen, Nathachit Limjunyawong, Jianzhong Xu, Zehua Zhang, Fei Luo, Ce Dou   +12 more
wiley   +1 more source

Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials

Advanced NanoBiomed Research, EarlyView.
Black and violet phosphorus‐based biomaterials exhibit broad‐spectrum antibacterial efficacy in various infections, including bone, skin, ocular, dental, lung, and sepsis cases. Their antibacterial mechanisms include physical disruption, light‐driven effects, targeted drug delivery, and enhanced composite strategies.
Zhuo Dai, Yu Zhang, Xiaoye Li, Ao He, Qiang Li, Weijun Xiu, Yongbin Mou, Heng Dong, Meng Ding   +8 more
wiley   +1 more source

Drug delivery strategies to improve the treatment of corneal disorders

Heliyon
Anterior eye disorders including dry eye syndrome, keratitis, chemical burns, and trauma have varying prevalence rates in the world. Classical dosage forms based-topical ophthalmic drugs are popular treatments for managing corneal diseases.
Mahsa Fallah Tafti, Zeinab Fayyaz, Hossein Aghamollaei, Khosrow Jadidi, Shahab Faghihi   +4 more
doaj   +1 more source

Ocular pharmacoscintigraphic and aqueous humoral drug availability of ganciclovir-loaded mucoadhesive nanoparticles in rabbits [PDF]

, 2013
The present report describes the improved ocular retention and aqueous humoral drug availability of ganciclovir (GCV) when administered via topical instillation of different kind of nanoparticles onto the rabbit eye.
Ahmad, Farjam Jalees, Ahmad, Mohammad Zaki, Akhter, Sohail, Bhatnagar, Aseem, Rahman, Ziyaur, Ramazani, Farshad, Storm, Gert   +6 more
core   +2 more sources

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Contact lenses as drug controlled release systems: a narrative review

Revista Brasileira de Oftalmologia, 2016
Topically applied therapy is the most common way to treat ocular diseases, however given the anatomical and physiological constraints of the eye, frequent dosing is required with possible repercussions in terms of patient compliance.
Helena Prior Filipe, José Henriques, Pedro Reis, Pedro Cruz Silva, Maria João Quadrado, Ana Paula Serro   +5 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]

, 2015
PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David, Arana, Eloisa, Buitrago, Emiliano, Chantada, Guillermo Luis, Croxatto, Juan Oscar, del Sole, Maria Jose, Djaballah, Hakim, Francis, Jasmine, Laurent, Viviana Eunice, Mena, Hebe Agustina, Negrotto, Soledad, Schaiquevich, Paula Susana, Sgroi, Mariana, Winter, Ursula Andrea   +13 more
core   +2 more sources

The Carbon Number‐specific Impact of Mineral Oil Saturated Hydrocarbons on Inducing Colonic Inflammation in Female and Male Fischer 344 Rats

Food Frontiers, EarlyView.
MOSH‐induced colonic alterations and sex‐specific metabolic pathways in female and male F344 rats. ABSTRACT This study investigated the effects of mineral oil saturated hydrocarbon (MOSH) sub‐fractions (C20‐30 and C30‐50) on the colon of male and female F344 rats and the underlying mechanisms.
Lin Zhu, Mingming Zhang, Hong Zhang, Hai Zhang, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang   +6 more
wiley   +1 more source