Results 21 to 30 of about 36,524 (294)
Therapeutic applications of contact lens-based drug delivery systems in ophthalmic diseases
Drug Delivery, 2023 Traditional ophthalmic drugs, such as eye drops, gels and ointments, are accompanied by many problems, including low bioavailability and potential drug side effects.
Lianghui Zhao +5 more
doaj +1 more source
Mucoadhesive microparticles engineered for ophthalmic drug delivery [PDF]
Journal of Physics and Chemistry of Solids, 2007 Although topical drug delivery is a convenient route of administration to treat various eye diseases, it has serious limitations due to rapid clearance of the formulation from the surface of the eye. In this study, we engineered microparticles for both sustained drug delivery and prolonged residence time on the extraocular surface.
Young Bin Choy +2 more
openalex +4 more sources
Nanofibers as a drug carrier in ophthalmic therapy [PDF]
Farmacja Polska, 2021 In ophthalmic therapy, drugs of various structures are used, administered into the conjunctival sac or onto the cornea. Novel concepts of technological development of the form of an ophthalmic drug delivery systems include obtaining a higher ...
Anna Czech +2 more
doaj +1 more source
Cell Reports Physical Science, 2020 Summary: Infectious endophthalmitis is a growing concern that causes irreversible intraocular tissue and optic nerve damage. Here, we report a theranostic nanoplatform based on UiO-66-NH2 to combine photodynamic therapy (PDT) and lipopolysaccharide (LPS)
Yingying Jin +9 more
doaj +1 more source
Diffusion-Based Design of Multi-Layered Ophthalmic Lenses for Controlled Drug Release. [PDF]
PLoS ONE, 2016 The study of ocular drug delivery systems has been one of the most covered topics in drug delivery research. One potential drug carrier solution is the use of materials that are already commercially available in ophthalmic lenses for the correction of ...
Andreia F R Pimenta +5 more
doaj +1 more source
A Review on Conventional and Novel Topical Ocular Drug Delivery System
Journal of Pharmacy, 2021 Ocular drug delivery is a very challenging area for ophthalmologists and drug delivery scientists due to the structural and barrier complexity of the eye.
Mohamad Faeznudin Rozi +1 more
doaj +1 more source
MedComm – Biomaterials and Applications, 2023 Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been used as suitable carriers for ophthalmic drug delivery. Drug molecules can be either encapsulated or chemically coupled to dendrimers.
Juan Wang +3 more
doaj +1 more source
Nanoparticles in ocular applications and their potential toxicity
Frontiers in Molecular Biosciences, 2022 Nanotechnology has been developed rapidly in recent decades and widely applied in ocular disease therapy. Nano-drug delivery systems overcome the bottlenecks of current ophthalmic drug delivery and are characterized with strong biocompatibility ...
Cao Yang +14 more
doaj +1 more source
Trojan Microparticles Potential for Ophthalmic Drug Delivery [PDF]
Current Medicinal Chemistry, 2019 The administration of drugs to treat ocular disorders still remains a technological challenge in this XXI century. Although there is an important arsenal of active molecules useful to treat ocular diseases, ranging from classical compounds to biotechnological products, currenty, no ideal delivery system is able to profit all their therapeutic ...
Sergio Esteban-Pérez +4 more
openalex +5 more sources
A Randomized, Double-Blinded, Placebo-Controlled, Cross Over Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine [PDF]
, 2020 Introduction. Daily oral beta-adrenoreceptor antagonist has been shown to be effective in preventing migraine headaches. Timolol 0.5% ophthalmic solution is a non-selective beta-adrenoreceptor antago- nist, where the primary use is for glaucoma.
Aggarwal, Dipika +10 more
core +2 more sources