Results 71 to 80 of about 133,922 (249)

Opium trade and the spread of HIV in the Golden Crescent

Harm Reduction Journal, 2017
The Golden Crescent region of South Asia—comprising Afghanistan, Iran, and Pakistan—is a principal global site for opium production and distribution. Over the past few decades, war, terrorism, and a shifting political landscape have facilitated an active
Syeda Ayesha Farooq, Mohammad Hafiz Rasooly, Syed Hani Abidi, Kayvon Modjarrad, Syed Ali   +4 more
doaj   +1 more source

Emergence of Medetomidine in the Unregulated Drug Supply and Its Association With Hallucinogenic Effects

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction The unregulated drug supply in the United States is rapidly evolving, and veterinary tranquillisers have emerged as adulterants of concern, especially in illicitly‐manufactured fentanyl. Following the proliferation of xylazine, medetomidine, a more potent sedative, has recently appeared in multiple US states.
Adams L. Sibley, Madigan L. Bedard, Samuel Tobias, Brooke A. Chidgey, Irina G. Phillips, Alice Bell, Nabarun Dasgupta   +6 more
wiley   +1 more source

Opiate substitution treatment combined with appropriate psychosocial interventions. [PDF]

, 1999
This paper outlines the benefits of several opiate agonists in reducing health risks and criminal behaviour. The paper focuses not only methadone programmes, but also the use of newer mu ophoid agonists such as levo-alpha-acetylmethadol (LAAM), which has
Farrell, Michael, Marsden, John
core  

Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients - Frequency and correlates of use [PDF]

, 2003
This retrospective study aims to determine whether there is a difference in the additional consumption of alcohol between addicts treated with methadone or dihydrocodeine (DHC) and untreated addicts injecting heroin.
Backmund, Markus, Eichenlaub, Dieter, Meyer, Kirsten, Schütz, Christian G., Soyka, Michael   +4 more
core   +1 more source

ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14

AIDS Research and Therapy, 2012
Background Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on adherence is unknown.
Rosen Marc I, Black Anne C, Arnsten Julia H, Simoni Jane M, Wagner Glann J, Goggin Kathleen, Remien Robert H, Golin Carol E, Wang Yan, Bangsberg David, Liu Honghu H   +10 more
doaj   +1 more source

Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent

Experimental Physiology, EarlyView.
Abstract Oestradiol (17β‐E2) is reported to prolong the cardiac action potential duration and QT interval, in part by affecting cardiac ion channels. Previous studies found inhibiting 17β‐E2 effects on the repolarizating cardiac KV7.1/KCNE1 channel, or its native current, in heterologous expression systems or tissue from animal species.
Veronika A. Linhart, Lucas Dauga, Sara I. Liin   +2 more
wiley   +1 more source

Integrated treatment of hepatitis C virus infection among people who inject drugs: study protocol for a randomised controlled trial (INTRO-HCV)

BMC Infectious Diseases, 2019
Background A large proportion of people who inject drugs (PWID) living with hepatitis C virus (HCV) infection have not been treated. It is unknown whether inclusion of HCV diagnostics and treatment into integrated substance use disorder treatment and ...
Lars T. Fadnes, Christer Frode Aas, Jørn Henrik Vold, Christian Ohldieck, Rafael Alexander Leiva, Fatemeh Chalabianloo, Svetlana Skurtveit, Ole Jørgen Lygren, Olav Dalgård, Peter Vickerman, Håvard Midgard, Else-Marie Løberg, Kjell Arne Johansson, for the INTRO-HCV Study Group   +13 more
doaj   +1 more source

Urothelial carcinoma: Perioperative considerations from top to bottom

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Urothelial carcinoma is an aggressive entity that is associated with significant morbidity, but there have been major advances in both our understanding of and treatment options for patients with this disease. In this review, the authors focus on novel therapeutic and diagnostic approaches in the perioperative setting, with an emphasis on ...
Wesley Yip, Salvador Jaime‐Casas, Anjaney Kothari, Mary Sullivan, Leslie K. Ballas, Domenique Escobar, Anne K. Schuckman, Jonathan E. Rosenberg, Jonathan A. Coleman   +8 more
wiley   +1 more source

Drug‐Related Engrams and Their Role in the Persistence and Recurrence of Drug‐Related Behaviors

Hippocampus, Volume 35, Issue 6, November 2025.
ABSTRACT Memory is a cornerstone of human behavior, and addiction offers a compelling model of its persistence and plasticity. The scope of engram research has rapidly expanded to include addiction‐related phenomena. Addiction‐related memories, like strong aversive memories, are often highly resistant to extinction and can continue to drive relapse ...
M. Cutler, A. Thati, S. L. Grella
wiley   +1 more source

Changes in substance use during outpatient treatment for substance use disorders: a prospective Norwegian cohort study from 2016 to 2020

Substance Abuse Treatment, Prevention, and Policy, 2021
Background Continuous use of amphetamines, alcohol, benzodiazepines, cannabis, cocaine, or opioids contributes to health impairments, increased morbidity, and overdose deaths among patients with substance use disorders (SUDs).
Jørn Henrik Vold, Fatemeh Chalabianloo, Christer F. Aas, Else-Marie Løberg, Kjell Arne Johansson, Lars Thore Fadnes   +5 more
doaj   +1 more source