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CNS Drugs, 2020 The ongoing opioid crisis, now into its second decade, represents a global public health challenge. Moreover, the opioid crisis has manifested despite clinical access to three approved opioid use disorder medications: the full opioid agonist methadone ...
E. Townsend, M. Banks
semanticscholar +1 more source
Pain sensitivity and observer perception of pain in individuals with autistic spectrum disorder [PDF]
, 2013 The peer-reviewed literature investigating the relationship between pain expression and perception of pain in individuals with ASD is sparse. The aim of the present systematic PRIMSA review was twofold: first, to see what evidence there is for the widely
Allely, C.S.
core +4 more sources
Substance Abuse Treatment, Prevention, and Policy, 2022 Background People living in rural and remote communities in Canada are often disproportionately impacted by opioid use disorder. When compared to urban centres, rural and remote populations face additional barriers to treatment, including geographical ...
Em M. Pijl +9 more
doaj +1 more source
Management of opioid use disorders: a national clinical practice guideline
Canadian Medical Association Journal, 2018 [See related article at [www.cmaj.ca/lookup/doi/10.1503/cmaj.180209][2]][2] KEY POINTS Opioid use disorder is one of the most challenging forms of addiction facing the Canadian health care system, and a major contributor to the marked rises in opioid ...
J. Bruneau +7 more
semanticscholar +1 more source
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
, 2018 Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová +6 more
wiley +1 more source
Comparison of Early Maladaptive Schemas and Parenting Origins in Patients with Opioid Abuse and Non-Abusers [PDF]
Iranian Journal of Psychiatry, 2011 "nObjective: The aim of this study was to examine the difference of early maladaptive schemas and parenting origins in opioid abusers and non-opioid abusers. "nMethod: The early maladaptive schemas and parenting origins were compared in 56 opioid abusers
Ali Reza Kakavand +3 more
doaj +2 more sources
Effects of Substance Use, Recovery, and Non–Drug-Related Online Community Participation on the Risk of a Use Episode During Remission From Opioid Use Disorder: Longitudinal Observational Study [PDF]
, 2022 Elahe Naserianhanzaei, Miriam Koschate
openalex +1 more source
Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. [PDF]
, 2016 ObjectiveProton magnetic resonance spectroscopy (1H MRS) in opiate dependence showed abnormalities in neuronal viability and glutamate concentration in the anterior cingulate cortex (ACC).
Abé, Christoph +5 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside +5 more
wiley +1 more source