Results 111 to 120 of about 574,925 (310)

Update on the clinical use of buprenorphine: in opioid-related disorders.

open access: yesCanadian family physician Medecin de famille canadien, 2012
To review the current evidence on buprenorphine-naloxone for the treatment of opioid-related disorders, with a focus on primary care settings.MEDLINE and the Cochrane Database of Systematic Reviews were searched. Evidence is mainly level I.Buprenorphine is a partial μ-opioid agonist and κ-opioid antagonist with a long half-life and less abuse potential
Simon, Ducharme   +2 more
openaire   +1 more source

Predicting the Risk of Opioid Use Disorder Based on Early Maladaptive Schemas

open access: yesAmerican Journal of Men's Health, 2018
Substance use is a globally devastating social problem. Early maladaptive schemas (EMSs) are inefficient mechanisms leading directly or indirectly to psychological distress.
Somayeh Zamirinejad   +4 more
doaj   +1 more source

Is There Less Opioid Abuse in States Where Marijuana Has Been Decriminalized, Either for Medicinal or Recreational Use? A Clin-IQ

open access: yesJournal of Patient-Centered Research and Reviews, 2019
Opioid use, abuse, and associated mortality have reached an epidemic level. In some states, cannabis is being used to treat chronic pain. To examine the hypothesis that medical marijuana legislation may reduce adverse opioid-related outcomes if patients ...
Aaron M. Wendelboe   +6 more
doaj   +1 more source

Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová   +6 more
wiley   +1 more source

Emergency department management of opioid use disorder in pediatric patients

open access: yesJournal of the American College of Emergency Physicians Open
Opioid use disorder (OUD) has emerged as a significant public health crisis affecting individuals across all age groups. However, there remains a critical gap in understanding the specific nuances and challenges associated with OUD in pediatric ...
Evan S. Schwarz   +8 more
doaj   +1 more source

Providing Personalized Genetic Feedback for Psychiatric and Substance Use Disorders: An Urgent Need for Research

open access: yes
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
Danielle M. Dick, Jehannine (J9) Austin
wiley   +1 more source

Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri   +5 more
wiley   +1 more source

Impact of cannabidiol on reward- and stress-related neurocognitive processes among individuals with opioid use disorder: A pilot, double-blind, placebo-controlled, randomized cross-over trial [PDF]

open access: gold, 2023
Joji Suzuki   +7 more
openalex   +1 more source

Corticotrophin-releasing hormone binding protein in the basolateral amygdala: divergent roles in cocaine and opioid addiction like behaviors

open access: yesAddiction Neuroscience
Cocaine and oxycodone use disorders represent urgent public health burdens, with limited treatment options for opioid dependence and no approved pharmacotherapies for cocaine-related disorders, highlighting the critical need to uncover novel molecular ...
Courtney P. Wood   +9 more
doaj   +1 more source

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside   +5 more
wiley   +1 more source

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