Results 141 to 150 of about 648,698 (363)

Corticotrophin-releasing hormone binding protein in the basolateral amygdala: divergent roles in cocaine and opioid addiction like behaviors

Addiction Neuroscience
Cocaine and oxycodone use disorders represent urgent public health burdens, with limited treatment options for opioid dependence and no approved pharmacotherapies for cocaine-related disorders, highlighting the critical need to uncover novel molecular ...
Courtney P. Wood, Arnav Gurha, Caitlin Crook, Angelica Martinez, Selen Dirik, Cloe Moreno, Anirudh Vaiyapuri, Avraham Libster, Francesca Telese, Giordano de Guglielmo   +9 more
doaj   +1 more source

Early COVID-Related pandemic impacts and subsequent opioid outcomes among persons receiving medication for opioid use disorder: a secondary data analysis of a Type-3 hybrid trial [PDF]

, 2023
Tim Janssen, Bryan R. Garner, Julia Yermash, Kimberly R. Yap, Sara J. Becker   +4 more
openalex   +1 more source

A QUALITY IMPROVEMENT STUDY OF THE implimentation of the VERMONT NEWBORN PLAN OF SAFE CARE AMONG NURSING STAFF AT VERMONT HOSPITALS [PDF]

, 2019
PURPOSE: The purpose of this quality improvement needs assessment was to evaluate the implementation of the Vermont Newborn Plan of Safe Care (VNPSC) since its introduction 17 months ago. These plans were created in response to federal mandates to create
Buley, Annik
core   +1 more source

Unique Transcriptional Profile of Sustained Ligand-Activated Preconditioning in Pre- and Post-Ischemic Myocardium [PDF]

, 2013
BACKGROUND: Opioidergic SLP (sustained ligand-activated preconditioning) induced by 3–5 days of opioid receptor (OR) agonism induces persistent protection against ischemia-reperfusion (I-R) injury in young and aged hearts, and is mechanistically distinct
Ashton, Kevin J., Headrick, John P., Kiessling, Can J., Peart, Jason N., See Hoe, Louise E., Tupicoff, Amanda, Williams-Pritchard, Grant   +6 more
core   +3 more sources

Providing Personalized Genetic Feedback for Psychiatric and Substance Use Disorders: An Urgent Need for Research

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
Danielle M. Dick, Jehannine (J9) Austin
wiley   +1 more source

Cytochrome P450 2D6 *17 and *29 Allele Activity for Risperidone Metabolism: Advancing Precision Medicine Health Equity

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2D6 alleles with low frequency in Eurocentrically biased study populations are often excluded from pharmacogenetic investigation and consequently may have misassigned activity values. This health inequity may be contributing to imprecise dose predictions for CYP2D6‐metabolizing drugs.
Oyinlade Kehinde, Samuel E. Vaughn, Ogochukwu Amaeze, Paul Toren, Brandon Retke, Akinyemi Oni‐Orisan, Laura B. Ramsey   +6 more
wiley   +1 more source

Health-Related Quality of Life and Recovery Capital Among Recovery Residents Taking Medication for Opioid Use Disorder in Texas [PDF]

, 2023
Elizabeth O. Obekpa, Sheryl McCurdy, Vanessa Schick, Christine Markham, J. Michael Wilkerson   +4 more
openalex   +1 more source

Opioid Use Disorders: Perioperative Management of a Special Population

Anesthesia and Analgesia, 2018
Opioid-related overdose deaths have reached epidemic levels within the last decade. The efforts to prevent, identify, and treat opioid use disorders (OUDs) mostly focus on the outpatient setting.
E. N. Ward, A. Quaye, T. Wilens
semanticscholar   +1 more source

A Roadmap for Integrating Neuroscience into Addiction Treatment:A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine [PDF]

, 2019
Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice.
Arunogiri, Shalini, Baldacchino, Alex, Bates, Marsha E., Bowden-Jones, Henrietta, Bruno, Raimondo, Campanella, Salvatore, Daughters, Stacey, Ekhtiari, Hamed, Hester, Rob, Kouimtsidis, Christos, Lorenzetti, Valentina, Lubman, Dan I., Manning, Victoria, Meyerhoff, Dieter J., Moeller, Scott J., Paulus, Martin P., Pennington, David, Piercy, Hugh, Ralph, Annaketurah, Rezapour, Tara, Steele, Douglas, Tavakoli, Hosna, Tolomeo, Serenella, Verdejo-Garcia, Antonio, Zare-Bidoky, Mehran, Zilverstand, Anna   +25 more
core   +6 more sources

Pharmacomicrobiomics

Clinical Pharmacology &Therapeutics, EarlyView.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich, Naama Geva‐Zatorsky, Rachel Herren, Libusha Kelly, Ziv Cohen, Haiying Zhou, Yi‐Ching Chen, Khalid Shah, Talin A. Robinson‐Catala, Grecia Frisby, Jason H. Karnes, Lisl Shoda   +11 more
wiley   +1 more source