Results 201 to 210 of about 10,513,249 (295)

The evolving epidemiology of opioid use disorder: polysubstance use, drug supply transformation, and policy implications. [PDF]

Front Public Health
Mandapati NK, Tovar DC, Bindlish R, Hernandez YL, Alves MJ, Baum MK, Aggarwal S.   +6 more
europepmc   +1 more source

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

Addiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam, Mohammad Karamouzian, Michael John Milloy, Carmen Verdicchio, Eric C. Sayre, Kanna Hayashi, Thomas Kerr, Kora DeBeck   +7 more
wiley   +1 more source

Prescribed alternative stimulants among people who use unregulated stimulants: Examining the association between maximum dose reached and medication discontinuation in the first 3 years of implementation in British Columbia, Canada

Addiction, EarlyView.
Abstract Background and aims In 2020, British Columbia (BC), Canada, introduced ‘Prescribed Alternatives’ (PA) as an approach to offering regulated substances to people accessing the unregulated supply. This study aimed to estimate and compare prescribing characteristics of dextroamphetamine and methylphenidate stimulant PAs in BC, to estimate ...
Bin Zhao, Kevin Hu, Roshni Desai, Shania Au, Kali‐olt Sedgemore, Vitor Tardelli, Addie Carter, Paxton Bach, Christian Schutz, Amanda Slaunwhite, Alexis Crabtree, Heather Palis   +11 more
wiley   +1 more source

Joint associations of recovery capital and polygenic risk with electronic health record observed remission and relapse in substance use disorder: Longitudinal evidence from the All of Us research program

Addiction, EarlyView.
Abstract Background and aims Recovery capital and genetic liability may be related to substance use disorder (SUD) remission through psychosocial and biologic pathways, but their joint association with remission course remains poorly understood. This question is clinically important because people entering remission differ in recovery resources and ...
Janaka V. Kosgolla, Douglas C. Smith
wiley   +1 more source

Clinicians' and people who use drugs' perspectives on artificial intelligence in addiction medicine

Addiction, EarlyView.
Abstract Background and aims Artificial intelligence (AI) may improve addiction medicine workflows and health outcomes but raises questions about data privacy and unintended harms for people who use drugs (PWUD). This qualitative study aimed to understand the perspectives of clinicians and PWUD regarding perceived benefits and concerns about clinical ...
Patrick J. A. Kelly, Elizabeth Chen, Amelia Bailey, Katie Biello, Brandon D. L. Marshall, Josiah D. Rich, Jaclyn M. W. Hughto   +6 more
wiley   +1 more source

Non-pharmacological interventions for opioid use disorder: protocol for a systematic review and network meta-analysis. [PDF]

Front Public Health
Li M, Miao D, Mo Q, Chen Q, Lu L.
europepmc   +1 more source

A framework to determine naloxone saturation with simulation modeling and cost‐effectiveness methods

Addiction, EarlyView.
Abstract Background and aims Jurisdictions lack practical tools to determine data‐informed naloxone saturation targets that account for local overdose dynamics and resource constraints. We aimed to introduce a generalizable framework that integrates simulation modeling with cost‐effectiveness principles to identify local naloxone saturation targets ...
Zongbo Li, Leah C. Shaw, Carolyn J. Park, Alexander Y. Walley, Czarina N. Behrends, Bruce R. Schackman, Brandon D. L. Marshall, Xiao Zang   +7 more
wiley   +1 more source

Associated prognostic impact of opioid use before Transcatheter aortic valve implantation - A Danish nationwide cohort study. [PDF]

Int J Cardiol Heart Vasc
Meibom M, Petersen JK, Mikkelsen V, Sørensen LM, Povlsen JA, Terkelsen CJ, Eftekhari A, Schou M, Køber L, de Backer O, Fosbøl E.   +10 more
europepmc   +1 more source

A decade of cannabis‐related hospital admissions in Victoria, Australia: A retrospective observational study

Addiction, EarlyView.
Abstract Background and aims Over the past decade, there has been increased lifetime use of illicit and medical cannabis, underscoring the need to examine public health impacts. This includes reports of increased cannabis‐related psychosis. In this context, this study aimed to determine all cannabis‐related hospital admissions in Victoria, Australia ...
Myfanwy Graham, Janneke Berecki‐Gisolf, Jane Hayman, Adrian Carter, Shalini Arunogiri, Suzanne Nielsen   +5 more
wiley   +1 more source