Results 211 to 220 of about 574,925 (310)
Circumstances surrounding opioid toxicity deaths within shelters in Ontario, Canada, before and during the COVID-19 pandemic: a population-based descriptive cross-sectional study. [PDF]
Hamzat B+12 more
europepmc +1 more source
Drug‐facilitated crime: A review of findings between 2019 and 2023
Abstract Drug‐facilitated crime (DFC) is a criminal act (e.g., assault, robbery, or sexual assault) in which the perpetrator uses drugs to impair the victim's ability to resist, remember, or recognize the crime being committed. Ethanol is commonly implicated in DFC casework, but limited data are published on other substances currently implicated in ...
Meaghan R. Hessler+2 more
wiley +1 more source
Abstract Background The increasing prevalence of dementia poses significant challenges for emergency department (ED) care, as persons living with dementia (PLWD) more frequently experience adverse outcomes such as delirium, prolonged stays, and higher mortality rates.
Sangil Lee+20 more
wiley +1 more source
Disrupted circadian rhythms and opioid-mediated adverse effects: Bidirectional relationship and putative mechanisms. [PDF]
Mehranfard N, Ghasemi M, Saboory E.
europepmc +1 more source
ABSTRACT Objectives Identifying predictors of increased healthcare utilization for hyperglycemia may have important implications for designing interventions to improve patient outcomes and reduce costs. Studies examining predictors of 30‐day recurrent ED hyperglycemia visits have been limited due to their retrospective nature.
Justin W. Yan+8 more
wiley +1 more source
Targeting dependence‐ and/or stress‐escalated alcohol drinking could help patients with alcohol use disorder (AUD). We found that reducing the activity of the epigenetic regulatory enzyme G9a (aka euchromatic histone‐lysine N‐methyltransferase 2 or EHMT2) either by a viral knockdown in the nucleus accumbens (NAc) or by repeated systemic administration ...
Marcelo F. Lopez+4 more
wiley +1 more source
Participants described several challenges seeking treatment for alcohol use disorder (AUD), including multiple prior treatment attempts, delayed recognition of problematic alcohol use, and incongruent treatment expectations and experiences. Those with executive functioning challenges (53%) described the need to self‐advocate and frustration with ...
Cayley Russell+39 more
wiley +1 more source
This real‐world study assessed whether varenicline improves outcomes in patients with ALD and AUD. Using data from a large electronic health record network, 1278 matched patients were analyzed. Varenicline use was associated with reduced all‐cause mortality and hepatic encephalopathy compared with FDA‐approved AUD therapies (acamprosate or naltrexone),
Pojsakorn Danpanichkul+10 more
wiley +1 more source
Exploring the role of gender on treatment outcomes in older adults with alcohol use disorder
This study found that older adults (60+ years) with alcohol use disorder (AUD) experienced substantial and sustained improvements in drinking outcomes 1 year after treatment. While women started with lower alcohol consumption, they showed smaller reductions over time compared to men, resulting in similar levels at follow‐up.
Jeppe Sig Juelsgaard Tryggedsson+5 more
wiley +1 more source
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall+8 more
wiley +1 more source