Results 131 to 140 of about 640,835 (387)

EudraVigilance insights: Suspected adverse drug reactions in infants through breastfeeding

British Journal of Clinical Pharmacology, EarlyView.
Aims We aimed to describe suspected adverse drug reactions (ADRs) in infants resulting from medications transmitted through mothers' milk, as reported to the European ADR database, EudraVigilance. The research sought to understand the frequency, seriousness and nature of these ADRs to assess potential risks associated with maternal medication use ...
Ida M. Heerfordt, Ditte Resendal Gotfredsen, Henrik Horwitz, Anette Kirstine Stark, Jon Trærup Andersen, Christina Gade, Ulrik Lausten‐Thomsen, Rasmus Huan Olsen   +7 more
wiley   +1 more source

Endogenous opioid peptides and the control of pain [PDF]

, 1979
H. W. Kosterlitz
openalex   +1 more source

Analgesic impact of intra‐operative opioids vs. opioid‐free anaesthesia: a systematic review and meta‐analysis

Anaesthesia, 2019
Opioids are administered peri‐operatively for postoperative analgesia, and intra‐operatively to control the sympathetic response to surgical stimuli, frequently as a surrogate for presumed pain.
J. Frauenknecht, K. Kirkham, A. Jacot-Guillarmod, E. Albrecht   +3 more
semanticscholar   +1 more source

Mind Your Meds: Safe Opioid Disposal Awareness [PDF]

, 2019
Driven by the effects of the opioid epidemic on friends, family members, students, and patients, members of the 2019 GEHLI Team “Mission Possible” are dedicated to bolstering educational awareness of safe leftover opioid disposal methods to decrease the ...
at Virginia Commonwealth University, The Grace E. Harris Leadership Institute, Davies, Mary Ann, Fox, Jenny, Johnson, Kenneth, Papenfuse, Jennifer, Schmitt, Michelle, Zhang, Shijun, Zoghby, Lori   +7 more
core   +1 more source

CASTNet: Community-Attentive Spatio-Temporal Networks for Opioid Overdose Forecasting

, 2019
Opioid overdose is a growing public health crisis in the United States. This crisis, recognized as "opioid epidemic," has widespread societal consequences including the degradation of health, and the increase in crime rates and family problems.
A Kennedy-Hendricks, A Kolodny, AM Ertugrul, DS Burke, H Jalal, M Pierce, M Warner, NB King, PJ Gruenewald, R Hammersley, RA Rudd, S Hochreiter, S Scardapane, T Bennett, T Seddon   +14 more
core   +1 more source

Developing the Inpatient Mental Health Pharmaceutical Assessment and Care Tool (IMPACT) for use by UK mental health pharmacy teams—a modified Delphi study

British Journal of Clinical Pharmacology, EarlyView.
Aims To develop an evidence‐ and consensus‐based patient prioritization tool for use by UK mental health inpatient pharmacy teams. Methods A modified‐Delphi technique was used to obtain experts' agreement on the content, design and practical use of the patient prioritization tool.
Fatima Q. Alshaikhmubarak, Richard N. Keers, Petra Brown, Penny J. Lewis   +3 more
wiley   +1 more source

Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States

JAMA Network Open, 2019
Key Points Question What is the projected effect of lowering incident nonmedical prescription opioid use on the future trajectory of the opioid overdose crisis in the United States?
Qiushi Chen, Marc R. Larochelle, D. T. Weaver, Anna Lietz, P. Mueller, S. Mercaldo, S. Wakeman, K. Freedberg, Tiana J. Raphel, Amy B. Knudsen, P. Pandharipande, J. Chhatwal   +11 more
semanticscholar   +1 more source

Pharmacology and relevant drug interactions of metamizole

British Journal of Clinical Pharmacology, EarlyView.
Metamizole is a frequently prescribed analgesic because of its favourable benefit/risk ratio compared with classic NSAIDs. However, increasing research shows that metamizole displays several drug interactions that are relevant to clinical practice. We reviewed the literature to summarize the pharmacology and most clinically relevant drug interactions ...
David J. Brinkman, Linda C. Hendriksen, Irma M. Rigter, Markus W. Hollmann   +3 more
wiley   +1 more source

Isolation and characterization of the opioid peptides from rat pituitary: beta-endorphin. [PDF]

, 1977
Menachem Rubinstein, S Stein, Sidney Udenfriend   +2 more
openalex   +1 more source

Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects

Nature Communications, 2019
Opioid analgesics are powerful pain relievers; however, over time, pain control diminishes as analgesic tolerance develops. The molecular mechanisms initiating tolerance have remained unresolved to date.
A. Kliewer, F. Schmiedel, S. Sianati, A. Bailey, J. Bateman, E. Levitt, John T. Williams, M. Christie, S. Schulz   +8 more
semanticscholar   +1 more source