Results 151 to 160 of about 697,718 (358)

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher   +12 more
wiley   +1 more source

The Effect of Probiotic Administration on the Level of Interleukin-6 and Interleukin-10 in Opioids Poisoned Patients Admitted to the Intensive Care Unit

open access: yesİstanbul Medical Journal
Introduction: Recent research has revealed that exposure to toxins and substances like cannabis, opium, heroin, and tramadol can inhibit the growth of lymphocytes.
Flora Aghababaee   +7 more
doaj   +1 more source

Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB‐5′Br‐PINACA, in Seized Herbal Materials

open access: yesDrug Testing and Analysis, EarlyView.
MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
Alexandre Barcia de Godoi   +6 more
wiley   +1 more source

Dopaminergic and Opioid Systems Interact to Produce Peripheral Antinociception in Mice

open access: yesJournal of Integrative Neuroscience
Background: The overall pain experience results from the balance between the nociceptive pathway and the body’s endogenous modulation of nociception. The interaction of these systems reduces nociception.
Bárbara F. G. Queiroz   +5 more
doaj   +1 more source

Efficacy and Safety of Lisdexamfetamine Versus Topiramate Versus Naltrexone/Bupropion in Individuals With Binge Eating Disorder: A Network Meta‐Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of lisdexamfetamine, topiramate, and naltrexone/bupropion for treating binge eating disorder (BED) using network meta‐analysis. Method We systematically searched PubMed, Scopus, ClinicalTrials.gov, and Cochrane Central up to February 2025 for randomized controlled trials evaluating these medications
Tamer Hodrob   +5 more
wiley   +1 more source

Dual‐Functional Food‐Derived Bioactive Peptides: Expanding Beyond Biological Activity

open access: yesFood Chemistry International, EarlyView.
This review examines recent advances in dual‐ and multifunctional food‐derived bioactive peptides, highlights emerging research integrating biological and techno‐functional properties, and offers perspectives to inform future studies in this field. ABSTRACT Food‐derived bioactive peptides (FBPs) are a diverse group of peptides with proven physiological
Cullen MacDonald, Xiaohong Sun
wiley   +1 more source

Reports of rising use of fentanyl in contemporary Brazil is of concern, but a US-like crisis may still be averted

open access: yesThe Lancet Regional Health. Americas, 2023
Francisco I. Bastos, Noa Krawczyk
doaj   +1 more source

Contextual risk among adolescents receiving opioid prescriptions for acute pain in pediatric ambulatory care settings

open access: green, 2020
Genevieve F. Dash   +4 more
openalex   +2 more sources

Increases in Drug and Opioid-Involved Overdose Deaths - United States, 2010-2015.

open access: yesMMWR. Morbidity and mortality weekly report, 2016
R. A. Rudd   +3 more
semanticscholar   +1 more source

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