Results 151 to 160 of about 659,970 (390)

Trends in opioid analgesic abuse and mortality in the United States.

New England Journal of Medicine, 2015
BACKGROUND The use of prescription opioid medications has increased greatly in the United States during the past two decades; in 2010, there were 16,651 opioid-related deaths.
Richard C. Dart, H. Surratt, Theodore J. Cicero, M. Parrino, S. Severtson, B. Bucher‐Bartelson, Jody L. Green   +6 more
semanticscholar   +1 more source

The synergistic effect of anticholinergic burden and depression on fall risk in older persons

British Journal of Clinical Pharmacology, EarlyView.
Aims Both anticholinergic burden (ACB) and depression are known to increase fall risk in older persons, next to increasing morbidity and mortality. However, the effect of depression on fall risk associated with ACB is unclear. This is relevant because several antidepressants have anticholinergic effects to some extent.
Raymond Salet, Nathalie van der Velde, Didi Rhebergen, Bob van de Loo, Lotta Seppala, Natasja M. van Schoor, Bruno Stricker, Marieke Henstra   +7 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States

JAMA Network Open, 2019
Key Points Question What is the projected effect of lowering incident nonmedical prescription opioid use on the future trajectory of the opioid overdose crisis in the United States?
Qiushi Chen, Marc R. Larochelle, D. T. Weaver, Anna Lietz, P. Mueller, S. Mercaldo, S. Wakeman, K. Freedberg, Tiana J. Raphel, Amy B. Knudsen, P. Pandharipande, J. Chhatwal   +11 more
semanticscholar   +1 more source

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson, Michelle Flood, Brian MacKenna, Emma Wallace, Fiona Boland, Ciara Kirke, Mary E. Walsh, Tom Fahey, Frank Moriarty   +8 more
wiley   +1 more source

Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

Ibrain, EarlyView., 2023
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju, Samyuktha Villavan, Saranya Ravi, Roja Murugesan, Panneerselvam Theivendren, Vennila Jaganathan, Redlin Jani Rajan, Krupanidhi Karunanithi   +7 more
wiley   +1 more source

Evaluating Adherence of Evidence-Based Post-Operative Discharge Opioid Prescribing Guidelines and Patient Outcomes Two Weeks Post-Discharge

Journal of Pain Research, 2022
Gerardo A Arwi,1,2 Penelope HR Tuffin,1 Stephan A Schug2 1Royal Perth Hospital, Perth, Western Australia, Australia; 2Anaesthesiology and Pain Medicine, University of Western Australia, Perth, Western Australia, AustraliaCorrespondence: Gerardo A Arwi ...
Arwi GA, Tuffin PHR, Schug SA
doaj  

Analgesic impact of intra‐operative opioids vs. opioid‐free anaesthesia: a systematic review and meta‐analysis

Anaesthesia, 2019
Opioids are administered peri‐operatively for postoperative analgesia, and intra‐operatively to control the sympathetic response to surgical stimuli, frequently as a surrogate for presumed pain.
J. Frauenknecht, K. Kirkham, A. Jacot-Guillarmod, E. Albrecht   +3 more
semanticscholar   +1 more source

Trends in drug–drug interaction prevalence and longitudinal associations with health outcomes in the older community‐dwelling population: Findings from The Irish LongituDinal study on Ageing

British Journal of Clinical Pharmacology, EarlyView.
Aims We estimate trends in severe drug–drug interaction (DDI) prevalence and examine longitudinal associations between DDI exposure and health outcomes (emergency department [ED] visits, quality‐of‐life [QoL] and functional decline) over approximately 10‐years in the older community‐dwelling population in Ireland.
John E. Hughes, Caitriona Cahir, Kathleen E. Bennett   +2 more
wiley   +1 more source

The Opioid Crisis in Rural and Small Town America [PDF]

, 2018
In this brief, authors Shannon Monnat and Khary Rigg examine rural versus urban differences in opioid mortality and identify challenges for dealing with the opioid crisis in rural areas.
Monnat, Shannon M, Rigg, Khary K
core   +1 more source