Results 71 to 80 of about 659,970 (390)

Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration

open access: yesArthritis Care &Research, Accepted Article.
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget   +7 more
wiley   +1 more source

The US Opioid Epidemic and Its Impact on US General Practice Veterinarians

open access: yesFrontiers in Veterinary Science, 2019
Objective: To assess the impact of the human opioid epidemic and associated shortages in drug supply on US general practice veterinarians.Design: Cross-sectional study.Sample: Members of the Veterinary Information Network (VIN).Procedures: An electronic ...
Lori Kogan   +3 more
doaj   +1 more source

Loperamide-Induced Ventricular Tachycardia Storm

open access: yesAvicenna Journal of Medicine, 2022
Loperamide is an over-the-counter antilaxative medication with minor opioid properties. For this reason, it has recently become a drug of concern for the Food and Drug Administration due to its potential for abuse.
William Giesing   +4 more
doaj   +1 more source

Promoting Awareness of the Opioid Epidemic in Rural Vermont [PDF]

open access: yes, 2017
Vermont is in the middle of an opioid epidemic. Heroin use fatalities are on the rise and the number of people in treatment for opioid use disorder in Rutland County has tripled in recent years.
Olson, Kathleen
core   +1 more source

How the presentation of patient information and decision-support advisories influences opioid prescribing behavior: A simulation study [PDF]

open access: yes, 2020
ObjectiveThe United States faces an opioid crisis. Integrating prescription drug monitoring programs into electronic health records offers promise to improve opioid prescribing practices.
Hussain, Mustafa I   +4 more
core  

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Evaluating the impact of a national naloxone programme on ambulance attendance at overdose incidents: a controlled time-series analysis [PDF]

open access: yes, 2017
Background and Aims: It has been suggested that distributing naloxone to people who inject drugs (PWID) will lead to fewer attendances by emergency medical services at opioid-related overdose incidents if peer administration of naloxone was perceived ...
Ashworth   +29 more
core   +2 more sources

Characteristics of Initial Prescription Episodes and Likelihood of Long-Term Opioid Use — United States, 2006–2015

open access: yesMMWR. Morbidity and mortality weekly report, 2017
Because long-term opioid use often begins with treatment of acute pain (1), in March 2016, the CDC Guideline for Prescribing Opioids for Chronic Pain included recommendations for the duration of opioid therapy for acute pain and the type of opioid to ...
Anuj Shah, C. Hayes, B. Martin
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Neuropeptides in the Extracellular Space of the Mouse Cortex Measured In Vivo by Nanodialysis Probe Coupled with LC‐MS

open access: yesAngewandte Chemie, EarlyView.
This study reveals a complex peptidomic landscape in the mouse somatosensory cortex, identifying locally released and potentially transported neuropeptides using a membrane‐free nanodialysis sampling probe coupled with nanoLC‐timsTOF mass spectrometry.
Keyin Li   +6 more
wiley   +2 more sources

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