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Opioid analgesics for chronic noncancer pain in patients prescribed opioid agonist therapy or with opioid use disorder: A systematic review [PDF]
Canadian Journal of PainBackground Opioid use disorder (OUD) is a growing public health concern in North America, often coexisting with chronic noncancer pain (CNCP). Managing both conditions presents unique challenges, highlighting the need for evidence to guide decision ...
Vahid Ashoorion +9 more
doaj +2 more sources
Subtypes in Patients Taking Prescribed Opioid Analgesics and Their Characteristics: A Latent Class Analysis [PDF]
Frontiers in Psychiatry, 2022 BackgroundOwing to their pharmacological properties the use of opioid analgesics carries a risk of abuse and dependence, which are associated with a wide range of personal, social, and medical problems.
Christian Rauschert +8 more
doaj +2 more sources
Opioid peptide-derived analgesics [PDF]
The AAPS Journal, 2005 Two recent developments of opioid peptide-based analgesics are reviewed. The first part of the review discusses the dermorphin-derived, cationic-aromatic tetrapeptide H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA, where Dmt indicates 2',6'-dimethyltyrosine), which showed subnanomolar mu receptor binding affinity, extraordinary mu receptor selectivity, and ...
Peter W. Schiller
openalex +5 more sources
Opioid analgesics: Managing the predictable [PDF]
Clinical MedicineIt is imperative for clinicians to understand the common adverse effects of opioid therapy and ensure patients are properly counselled on them prior to opioid initiation. Predictable adverse effects are wide ranging, and include bowel dysfunction, nausea,
A Barnes +2 more
doaj +2 more sources
Geographic Variation in the Prescription of Schedule II Opioid Analgesics among Outpatients in the United States [PDF]
Health Services Research, 2006 Lesley H Curtis, Raymond L Woosley
exaly +2 more sources
Health Promotion and Chronic Disease Prevention in Canada, 2021 IntroductionHarms caused by prescription opioid analgesics (POAs) have been identified as a major international public health concern. Recent statistics show rising numbers of opioid-related deaths across Canada.
Joshua Goodwin, Susan Kirkland
doaj +1 more source
Kidney Diseases, 2023 Introduction: Comprehensive data on the risk of hospital-acquired (HA) acute kidney injury (AKI) among adult users of opioid analgesics are lacking.
Mingjing Pi +27 more
doaj +1 more source
Adverse selection? A multi-dimensional profile of people dispensed opioid analgesics for persistent non-cancer pain. [PDF]
PLoS ONE, 2013 OBJECTIVES: This study investigates utilisation patterns for prescription opioid analgesics in the Australian community and how these are associated with a framework of individual-level factors related to healthcare use.
Kris D Rogers +3 more
doaj +1 more source
Pharmaceutics, 2021 The use of opioid analgesics in treating severe pain is frequently associated with putative adverse effects in humans. Topical agents that are shown to have high efficacy with a favorable safety profile in clinical settings are great alternatives for ...
Maksim Khotimchenko +4 more
doaj +1 more source
BMC Health Services Research, 2020 Background Dispensations of opioid analgesics to patients on opioid agonist therapy (OAT) may increase the risk of overdoses. The current study’s objectives are to investigate the dispensation rates and mean daily doses of dispensed opioid analgesics ...
Jørn Henrik Vold +4 more
doaj +1 more source