Results 151 to 160 of about 87,811 (348)

DEVELOPMENT OF COMPLEX PHARMACOTHERAPY OF SEVERE AND MODERATE PAIN. PART I. MULTITARGETED COMBINATION OF OPIOIDS AND NON-OPIOID ANALGESICS WITH CENTRAL EFFECTS

open access: yesРазработка и регистрация лекарственных средств, 2019
Medicines based on opioid analgesics are the basic means of pharmacotherapy of severe pain at present. Approaches to increase efficacy and safety of complex opioid analgesia are described and classified based on analysis of medicinal and veterinary ...
A. V. Sosnov   +4 more
doaj  

Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids. [PDF]

open access: yes, 2019
Tramadol is one of the most commonly used analgesics worldwide, classified as having a low abuse potential by U.S. Drug Enforcement Agency, and often recommended in pain management guidelines.
Abagyan, Ruben   +3 more
core   +1 more source

Opioid consumption after lower limb amputation in Medicare beneficiaries

open access: yesPM&R, EarlyView.
Abstract Background Despite targeted national quality improvement initiatives, opioid prescription and use patterns after lower limb amputation are not well studied. Objective To determine risk factors associated with extended opioid use and rates of high‐risk opioid prescribing after lower limb amputation. Design and setting A retrospective population‐
Alexander N. Khouri   +5 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Perceptions of Barriers to Using Opioid Analgesics: A Mixed Methods Study. [PDF]

open access: yesPalliat Med Rep, 2023
Aregay A   +4 more
europepmc   +1 more source

Quality of Postoperative Pain Management after Midfacial Fracture Repair—An Outcome-oriented Study [PDF]

open access: yes, 2015
Objectives There is a lack of literature regarding the procedure-specific quality of acute postoperative pain management after midfacial fracture repair.
Djedovic, Gabriel   +8 more
core   +2 more sources

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola   +9 more
wiley   +1 more source

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