Results 171 to 180 of about 57,069 (292)

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Resentful, Resigned and Respectful: Opioid Analgesics, Pain and Control, a Qualitative Study. [PDF]

Pharmacy (Basel)
Cooper R, Matheson C, Pagan E, Radford H.   +3 more
europepmc   +1 more source

How Motivations for Using Buprenorphine Products Differ From Using Opioid Analgesics: Evidence from an Observational Study of Internet Discussions Among Recreational Users (Preprint)

, 2019
Stephen F. Butler, Natasha K Oyedele, Taryn Dailey Govoni, Jody L. Green   +3 more
openalex   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Non-opioid analgesics for the prevention of chronic postsurgical pain: a systematic review and network meta-analysis. [PDF]

Br J Anaesth, 2023
Doleman B, Mathiesen O, Sutton AJ, Cooper NJ, Lund JN, Williams JP.   +5 more
europepmc   +1 more source

Backlash in the treatment of cancer pain: Use of opioid analgesics in a Finnish General Hospital in 1987, 1991, and 1994

, 1997
Eero Vuorinen, Anneli Vainio, Anssi Reponen   +2 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Timing of Naldemedine Initiation and Occurrence of Diarrhea in Patients Receiving Strong Opioid Analgesics: A Retrospective Study. [PDF]

Pharmacy (Basel)
Matsumoto T, Mura T, Wada T, Tsugo Y, Mukai N, Hamaoka T, Horita S, Semba Y, Watanabe S.   +8 more
europepmc   +1 more source

Availability and Use of Essential Opioid Analgesics in Sub-Saharan Africa: A Scoping Review Protocol. [PDF]

Int J Surg Protoc, 2023
Yao J, Ngo NV, Kibu OD, Asahngwa C, Jasmin HM, Gobina RM, Foretia DA.   +6 more
europepmc   +1 more source

P057: A systematic review of the efficacy of opioid analgesics for the management of acute pain in older adults in the emergency department [PDF]

, 2018
Jonathan Gravel, Mark E. DeVries, Daphne Horn, Shelley McLeod, Catherine Varner   +4 more
openalex   +1 more source