Pharmacogenetics of analgesic drugs [PDF]
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R +4 more
core +1 more source
Discontinuation of Long-term Opioid Analgesics was responsible for developing the HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics. Deborah (US Centers for and Christopher PharmD, DrPH and MPE
D. Dowell, W. Compton, B. Giroir
semanticscholar +1 more source
Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh +6 more
core +1 more source
Tapentadol extended release for the management of chronic neck pain [PDF]
BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Individual and county-level factors associated with use of multiple prescribers and multiple pharmacies to obtain opioid prescriptions in California. [PDF]
Use of multiple prescribers and pharmacies is a means by which some individuals misuse opioids. Community characteristics may be important determinants of the likelihood of this phenomenon independent of individual-level factors. This was a retrospective
Han, Huijun +3 more
core +5 more sources
Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina +6 more
core +2 more sources
Pain outcomes in patients with bone metastases from advanced cancer: assessment and management with bone-targeting agents [PDF]
Bone metastases in advanced cancer frequently cause painful complications that impair patient physical activity and negatively affect quality of life. Pain is often underreported and poorly managed in these patients.
A Kretzschmar +69 more
core +1 more source
Prescribing databases can be used to monitor trends in opioid analgesic prescribing in Australia [PDF]
Objective: There has been increased use of prescription opioid analgesics in Australia in the past 20 years with increasing evidence of related problems. A number of data sources collect information about the dispensed prescribing for opioid medications,
American Academy of Pain Medicine and the American Pain Society +36 more
core +1 more source
Objectives: Pain is considered the most common and debilitating symptom reported by patients affected by cancer, and opioids are at the front line for its effective management.
A. Charalambous +3 more
semanticscholar +1 more source

