Results 21 to 30 of about 410,228 (317)
Adverse selection? A multi-dimensional profile of people dispensed opioid analgesics for persistent non-cancer pain. [PDF]
PLoS ONE, 2013 OBJECTIVES: This study investigates utilisation patterns for prescription opioid analgesics in the Australian community and how these are associated with a framework of individual-level factors related to healthcare use.
Kris D Rogers +3 more
doaj +1 more source
Prenatal Opioid Analgesics and the Risk of Adverse Birth Outcomes
Epidemiology, 2021 Supplemental Digital Content is available in the text. Background: It is unclear whether confounding accounts for the increased risk of preterm birth and small for gestational age (SGA) birth in opioid analgesic exposed pregnancies.
Susan B. Brogly +5 more
semanticscholar +1 more source
Pharmaceutics, 2021 The use of opioid analgesics in treating severe pain is frequently associated with putative adverse effects in humans. Topical agents that are shown to have high efficacy with a favorable safety profile in clinical settings are great alternatives for ...
Maksim Khotimchenko +4 more
doaj +1 more source
BMC Health Services Research, 2020 Background Dispensations of opioid analgesics to patients on opioid agonist therapy (OAT) may increase the risk of overdoses. The current study’s objectives are to investigate the dispensation rates and mean daily doses of dispensed opioid analgesics ...
Jørn Henrik Vold +4 more
doaj +1 more source
PAIN Reports, 2022 . Introduction:. The opioid epidemic persists in the United States. The use of opioid medications is often assessed by claims data but potentially underestimated. Objectives:.
Yun Wang +5 more
doaj +1 more source
Orofacial pain in oncology: use of a new analgesic peptide tafalgin
Опухоли головы и шеи, 2023 In patients with head and neck tumors severe pain is more common than in patients with malignant neoplasms of other locations. At a third of patients, pain is the first characteristic of the disease, and after diagnosis, one half of the patients are ...
G. R. Abuzarova +6 more
doaj +1 more source
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog [PDF]
Eur J Pharmacol, 173174 (2020), 2020 Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on a molecular basis. Here, we examined the analgesic/adverse effect profile of a new NT(8-13) derivative denoted JMV2009, in which the Pro10 residue was substituted by a ...
arxiv +1 more source
Patterns of Routes of Administration and Drug Tampering for Nonmedical Opioid Consumption: Data Mining and Content Analysis of Reddit Discussions [PDF]
J Med Internet Res 2021;23(1):e21212, 2021 The complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and policies to effectively control its impact on public health.
arxiv +1 more source
BMJ Open, 2020 Objectives Many central nervous system (CNS) medications are considered potentially inappropriate for prescribing in older people; however, these medications are common in polypharmacy (≥5 medicines) regimens.
Natasha Slater +2 more
doaj +1 more source
Non-opioid Analgesics and the Endocannabinoid System
Balkan Medical Journal, 2020 Non-steroidal anti-inflammatory drugs produce antinociceptive effects mainly through peripheral cyclooxygenase inhibition. In opposition to the classical non-steroidal anti-inflammatory drugs, paracetamol and dipyrone exert weak anti-inflammatory ...
R. Topuz +3 more
semanticscholar +1 more source