Results 31 to 40 of about 410,228 (317)
Abuse-deterrent opioid analgesics: a guide for clinicians.
Pain Management, 2020 The US FDA has encouraged the development of abuse-deterrent formulations (ADFs) of opioid analgesics as one component in a comprehensive effort to combat prescription opioid abuse. Guidance issued by the FDA outlines three types of premarket studies for
A. Carinci
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Recent Chemical and Pharmacological Developments on 14-Oxygenated-N-methylmorphinan-6-ones
Molecules, 2021 Adequate pain management, particularly chronic pain, remains a major challenge associated with modern-day medicine. Current pharmacotherapy offers unsatisfactory long-term solutions due to serious side effects related to the chronic administration of ...
Mariana Spetea, Helmut Schmidhammer
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Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment
Frontiers in Psychiatry, 2022 IntroductionOver the last decade, the use of New/Novel Synthetic Opioids (NSO) has emerged as an increasing problem, and especially so in the USA. However, only little is known about the prevalence and history of NSO use in European heroin dependents ...
Michael Specka +13 more
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Prague Medical Report, 2013 The aim of prospective study was to evaluate the pain relief in the postoperative period and consumption of opioid and non-opioid analgesics as a risk factor of the anastomotic insufficiency after rectal and rectosigmoideal resection for carcinoma ...
S. Adámek +5 more
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Clinically important drug interactions with opioid and non-opioid analgesics [PDF]
Arhiv za farmaciju, 2018 Patients often seek advise from doctors and pharmacists about pain treatment. Opioid and non-opioid analgesics are the most commonly used drugs in the treatment of pain, but they have potential for pharmacodynamic and pharmacokinetic drug-drug ...
Vezmar-Kovačević Sandra +4 more
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Neuropsychopharmacology Reports, 2018 Aim Cancer pain impairs not only physical functions but also social functions and roles. Consequently, the overall health‐related quality of life of patients with cancer pain deteriorates. Opioid analgesics are recommended for treating moderate to strong
Yaeko Yokoshima +11 more
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Addressing the Global Tragedy of Needless Pain: Rethinking the United Nations Single Convention on Narcotic Drugs [PDF]
, 2007 The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries.
Allyn L. Taylor +11 more
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International Journal of Population Data Science, 2022 Background As dispensings for benzodiazepines and gabapentinoids have increased in recent years, risk of increased mortality has been identified, particularly when used with opioids. There is limited research examining use of these medicines among people
Chrianna Bharat +6 more
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Journal of the American Medical Association (JAMA), 2019 Discontinuation of Long-term Opioid Analgesics was responsible for developing the HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics. Deborah (US Centers for and Christopher PharmD, DrPH and MPE
D. Dowell, W. Compton, B. Giroir
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Controlled-release of opioids for improved pain management [PDF]
, 2016 The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioid drugs are most commonly used to counteract moderate to severe pain, but they are also increasingly accessed by patients with chronic non-malignant pain.
Ballet, Steven +5 more
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