Results 41 to 50 of about 57,069 (292)
Peripheralization Strategies Applied to Morphinans and Implications for Improved Treatment of Pain
Molecules, 2023 Opioids are considered the most effective analgesics for the treatment of moderate to severe acute and chronic pain. However, the inadequate benefit/risk ratio of currently available opioids, together with the current ‘opioid crisis’, warrant ...
Helmut Schmidhammer +3 more
doaj +1 more source
Materials and System Design for Self‐Decision Bioelectronic Systems
Advanced Materials, EarlyView.This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng +9 more
wiley +1 more source
Time to act for reappraising the educational system for universal access to opioid analgesics, for quality palliative care and cancer-related pain relief in East Asian countries [PDF]
, 2021 Masahiko Sumitani
openalex +1 more source
Advanced Science, EarlyView.Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li +13 more
wiley +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Acute chest syndrome (ACS) is one of the most common severe complications of sickle cell disease (SCD). In recent years, a major role of inflammation and innate immunity has been evidenced, but ACS pathophysiology remains incompletely understood, and therapeutic options are limited.
Slimane Allali +14 more
wiley +1 more source
PAIN Reports, 2018 . Introduction:. Cognitive performance and inflammation are altered in people with chronic low back pain (CLBP). Yet, the magnitude of these changes has been unclear because of the potential influence of opioid analgesics. Objectives:.
Georgia C. Richards +6 more
doaj +1 more source
Association of Timing and Duration of Prenatal Analgesic Opioid Exposure With Attention-Deficit/Hyperactivity Disorder in Children [PDF]
, 2021 Johanne Naper Trønnes +5 more
openalex +1 more source
Efficacy of Local Bupivacaine Injection of Postoperative Pain in Endoscopic Sinus Surgery
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Regional anesthesia is effective in alleviating postoperative pain and reducing the requirement for systemic pain medications. However, optimal postoperative pain management in endoscopic sinus surgery (ESS) remains challenging.
Wiracha Leewannapasai +4 more
wiley +1 more source
Molecules, 2020 Achieving effective pain management is one of the major challenges associated with modern day medicine. Opioids, such as morphine, have been the reference treatment for moderate to severe acute pain not excluding chronic pain modalities.
Abdelfattah Faouzi +2 more
doaj +1 more source
Psychoactive prescription drug use and misuse in patients on opioid agonist treatment
British Journal of Clinical Pharmacology, EarlyView.Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro +5 more
wiley +1 more source