Results 41 to 50 of about 410,228 (317)
IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics
Pharmacological Research, 2023 Though efficacious in managing chronic, severe pain, opioid analgesics are accompanied by significant adverse effects including constipation, tolerance, dependence, and respiratory depression.
Kyle J. Rehrauer +1 more
doaj
Prescribing and administration of opioid analgesics in residents of aged care facilities
Journal of Research in Pharmacy Practice, 2019 Objective: Optimal pain management in residents requires an understanding of prescribing and administration of opioid analgesics. This study aimed to describe opioid administration for elderly residents in a selection of aged care facilities.
Areej Numan Hussein, Lynne Emmerton
doaj +1 more source
Individualized Risk Assessment of Preoperative Opioid Use by Interpretable Neural Network Regression [PDF]
arXiv, 2022 Preoperative opioid use has been reported to be associated with higher preoperative opioid demand, worse postoperative outcomes, and increased postoperative healthcare utilization and expenditures. Understanding the risk of preoperative opioid use helps establish patient-centered pain management.
arxiv
Joint Distribution and Transitions of Pain and Activity in Critically Ill Patients [PDF]
, 2020 Pain and physical function are both essential indices of recovery in critically ill patients in the Intensive Care Units (ICU). Simultaneous monitoring of pain intensity and patient activity can be important for determining which analgesic interventions can optimize mobility and function, while minimizing opioid harm. Nonetheless, so far, our knowledge
arxiv +1 more source
Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]
, 2015 Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh +6 more
core +1 more source
Is this opioid analgesic tolerance?
Journal of Pain and Symptom Management, 1995 Tolerance to the analgesic effect of opioids is a poorly understood phenomenon. While generally accepted to be an uncommon problem, it clearly can present major management difficulties in some patients. This case report illustrates different aspects of tolerance, describes a management approach using different opioids, and provides a focus for ...
Robin L. Fainsinger, Eduardo Bruera
openaire +3 more sources
Investigating Dissemination of Scientific Information on Twitter: A Study of Topic Networks in Opioid Publications [PDF]
arXiv, 2021 One way to assess a certain aspect of the value of scientific research is to measure the attention it receives on social media. While previous research has mostly focused on the "number of mentions" of scientific research on social media, the current study applies "topic networks" to measure public attention to scientific research on Twitter.
arxiv
Managing Opioid-Tolerant Patients in the Perioperative Surgical Home. [PDF]
, 2016 Management of acute postoperative pain is important to decrease perioperative morbidity and improve patient satisfaction. Opioids are associated with potential adverse events that may lead to significant risk.
Baratta, Jaime L. +3 more
core +3 more sources
Improving Opioid Use Disorder Risk Modelling through Behavioral and Genetic Feature Integration [PDF]
arXiv, 2023 Opioids are an effective analgesic for acute and chronic pain, but also carry a considerable risk of addiction leading to millions of opioid use disorder (OUD) cases and tens of thousands of premature deaths in the United States yearly. Estimating OUD risk prior to prescription could improve the efficacy of treatment regimens, monitoring programs, and ...
arxiv
PLoS ONE, 2021 BackgroundShortages of opioid analgesics are increasingly common, interfere with patient care and increase healthcare cost. This study characterized the incidence of shortages of opioid analgesics in the period 2015-2019 and evaluated potential ...
Rosa Rodriguez-Monguio +2 more
doaj +1 more source