Results 51 to 60 of about 59,093 (301)

“I never realized how hard recovery is.” A quasi‐experimental evaluation of a youth participatory action research project for opioid prevention

American Journal of Community Psychology, EarlyView.
Abstract Youth participatory action research (YPAR) has been effectively used for substance use prevention. Yet, YPAR has not been evaluated for opioids, which negatively impact individuals and communities across the United States. The current study evaluated an opioid‐focused YPAR project.
Elizabeth H. Weybright, Katherine Hampilos, Alison J. White, Cassandra Grinstead, Jennifer Fees, Melanie Greer, Erica L. Doering, Laurie M. Graham   +7 more
wiley   +1 more source

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

Animal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin, Mathieu Magnin, Axel Aigle, Timothée Schuhler, Jean‐Yves Ayoub, Romain Lac, Charlotte Slek, Thomas Brichart, Abdessalem Hammed, Vanessa Louzier   +9 more
wiley   +1 more source

Differential expression of NPAS4 in the dorsolateral prefrontal cortex following opioid overdose

Drug and Alcohol Dependence Reports, 2022
Background: Although preclinical models reveal the neurobiological pathways altered through opioid abuse, comprehensive assessments of gene expression in human brain samples are needed.
David W. Sosnowski, Andrew E. Jaffe, Ran Tao, Amy Deep-Soboslay, Chang Shu, Sarven Sabunciyan, Joel E. Kleinman, Thomas M. Hyde, Brion S. Maher   +8 more
doaj   +1 more source

Opioid Addiction 2016 Facts & Figures [PDF]

, 2016
National Opioid Overdose Epidemic* Drug overdose is the leading cause of accidental death in the US, with 55,403 lethal drug overdoses in 2015. Opioid addiction is driving this epidemic, with 20,101 overdose deaths related to prescription pain relievers,

core  

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh, Eva Saar, Jennifer Pilgrim, Louisa Degenhardt, Lucinda Burns, Suzanne Nielsen, Wayne D Hall   +6 more
core   +1 more source

Opioid Prescribing Patterns Before Fatal Opioid Overdose [PDF]

American Journal of Preventive Medicine, 2020
Although opioid prescribing has decreased since 2010, overdose deaths involving illicit opioids have continued to rise. This study explores prescribing patterns before fatal overdose of decedents who died of prescription and illicit opioid overdoses.This retrospective cohort study was conducted in 2019 and included all 1,893 Illinois residents who died
Craig E. Berberet, Jennifer E. Layden, Elizabeth Salisbury-Afshar, Ali B Abbasi, Mai T. Pho   +4 more
openaire   +3 more sources

The use of international classification of diseases codes to identify hospital admissions linked with adverse drug events: Validation study

British Journal of Clinical Pharmacology, EarlyView.
Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová, Fatma Karapinar‐Çarkit, Daniala L. Weir   +2 more
wiley   +1 more source

Effectiveness of direct patient outreach with a narrative naloxone and overdose prevention video to patients prescribed long-term opioid therapy in the USA: the Naloxone Navigator randomised clinical trial

BMJ Public Health
Introduction Public health efforts to reduce opioid overdose fatalities include educating people at risk and expanding access to naloxone, a medication that reverses opioid-induced respiratory depression.
Jason M Glanz, Ingrid A Binswanger, Shane R Mueller, Komal J Narwaney, Nicole M Wagner, Stanley Xu, Courtney R Kraus, Kris Wain, Sheila Botts   +8 more
doaj   +1 more source

Urine Screening for Opiod and Illicit Drugs in the Total Joint Arthroplasty Population [PDF]

, 2020
Introduction. Recent studies have shown an increase in post-operative orthopaedic complications associated with pre-operative opioid use. It is, therefore, important to know if patients use opioids before scheduled surgery.
Bhargava, Tarun, Messamore, William, Schmanke, Ken, Trent, Jesse, Vopat, Matthew, Yang, Shang-You, Zackula, Rosey   +6 more
core   +2 more sources

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source