Results 191 to 200 of about 45,822 (323)
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 8, Issue 10, Page 1078-1093, October 2025.ABSTRACT The popularity of incretin‐based therapies has increased substantially over the past several years due to their clinically significant efficacy for weight loss and positive impact on weight‐related comorbid conditions, yet, few clinical practice guidelines for the management of overweight and obesity have been updated to incorporate these ...
Sara Lingow +6 more
wiley +1 more source
Influences of anti-inflammatory drugs on the opioid peptide content in the rat incisor pulp
, 1984 Teruo Kudo +3 more
openalex +2 more sources
Neuropharmacology: Effects on Rat Brain K1- and K2-Opioid Receptors after Chronic Treatment with Non-peptide K-Agonists [PDF]
, 1998 Mona M. McConnaughey +2 more
openalex +1 more source
G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers
MedComm, Volume 6, Issue 10, October 2025.G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan +6 more
wiley +1 more source
Morphinomimetic activities of novel endogenous opioid peptides
, 1981 Yujiro Hayashi +7 more
openalex +1 more source
Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
MedComm, Volume 6, Issue 10, October 2025.PROTACs are reshaping drug discovery through targeted protein degradation. Clinical programs now extend to prostate, breast, lung, hematologic, and solid tumors, with key targets including AR, ER, BTK, STAT3, Bcl‐xL, BRD9, Kras, and so on. These degraders overcome resistance, broaden therapeutic scope, and provide solutions for “undruggable” proteins ...
Gang Fan +9 more
wiley +1 more source
Opiate receptors and opioid peptides: "The poppies of the mind"
, 1982 B. Meyer
openalex +2 more sources
MedComm, Volume 6, Issue 10, October 2025.This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li +7 more
wiley +1 more source
Elf-pulsed magnetic fields modulate opioid peptide gene expression in myocardial cells [PDF]
, 2000 Carlo Ventura
openalex +1 more source