Results 191 to 200 of about 46,704 (314)

Emulating a Randomized Controlled Trial of Long‐Acting Insulins and Cardiovascular Events Using Real‐World Data for Patients With Type 2 Diabetes

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 1, January 2026.
ABSTRACT Aims Randomized controlled trials (RCTs) have high internal validity but often have limited generalizability. To our knowledge, there have been no previous studies emulating RCTs using real‐world data to evaluate the risk of major adverse cardiovascular events (MACE) among patients with type 2 diabetes mellitus (T2DM) treated with long‐acting ...
Wanning Wang, Pauline Reynier, Michael Webster‐Clark, Oriana H. Y. Yu, Vanessa Brunetti, Kristian B. Filion   +5 more
wiley   +1 more source

Stereospecific synthesis of (2S)-2-methyl-3-(2′,6′-dimethyl-4′-hydroxyphenyl)-propionic acid (Mdp) and its incorporation into an opioid peptide

, 2001
Yixin Lü, Grazyna Weltrowska, Carole Lemieux, Nga N. Chung, Peter W. Schiller   +4 more
openalex   +1 more source

Surface acoustic wave technology as a tool for functional characterization of new compounds [PDF]

, 2012
Bracke, Nathalie, Deneve, Laurens, De Spiegeleer, Bart   +2 more
core   +1 more source

14-O-Heterocyclic-substituted naltrexone derivatives as non-peptide mu opioid receptor selective antagonists: Design, synthesis, and biological studies

, 2008
Li Guo, Lindsey C. Aschenbach, Hengjun He, Dana E. Selley, Yan Zhang   +4 more
openalex   +1 more source

Glucagon‐like peptide‐1 receptor agonist and respiratory complications after endoscopy: A Japanese nationwide cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 316-323, January 2026.
Abstract Aims While discontinuation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) before esophagogastroduodenoscopy (EGD) is not universally mandated, safety concerns persist. Evidence remains insufficient for managing specific patient subgroups, particularly in Asian populations. We aimed to provide evidence for stratified risk assessment in
Hiroyuki Hisada, Kazuhiko Ikeuchi, Yosuke Tsuji, Nobutake Yamamichi, Naomi Kakushima, Kazuya Okushin, Seiichi Yakabi, Chihiro Takeuchi, Daisuke Ohki, Hiroya Mizutani, Yuko Miura, Dai Kubota, Takeya Tsutsumi, Mitsuhiro Fujishiro   +13 more
wiley   +1 more source

RELEASE OF OPIOID PEPTIDES IN ANAESTHETIZED CATS?

, 1980
Michael R. Dashwood, W. Feldberg
openalex   +2 more sources

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

Geriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi, Shuang Liu, Yasuyuki Suzuki, Yuuka Shibata, Shizuo Yamada   +4 more
wiley   +1 more source

Equipotent enantiomers of cyclic opioid peptides at μ opioid receptor. [PDF]

Pept Sci (Hoboken), 2019
Weltrowska G, Nguyen TM, Chung NN, Wilkes BC, Schiller PW.   +4 more
europepmc   +1 more source

A synthetic peptide, derived from neurotoxin GsMTx4, acts as a non-opioid analgesic to alleviate mechanical and neuropathic pain through the TRPV4 channel

Shao-Xi Ke, Ping Dong, Yunqing Mei, J Wang, Mingxi Tang, Wan-xin Su, Jingjing Wang, Chen Chen, Xiaohui Wang, Junwei Ji, Xin-Ran ZHuang, Shuangshuang Yang, Yun Zhang, Linda M. Boland, Meng Cui, Masahiro Sokabe, Zhe Zhang, Qiong‐Yao Tang   +17 more
openalex   +1 more source

Quercetin Alleviates Osteoarthritis Pain by Inhibiting Vascular Endothelial Growth Factor A Through Regulating cGAS/STING Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Knee osteoarthritis (KOA), a common degenerative joint disease marked by pain, inflammation and cartilage degradation, has been increasingly associated with dysregulated innate immune signalling. Among the implicated molecular pathways, cGAS/STING has emerged as a key modulator in both disease pathogenesis and therapeutic intervention ...
Enrui Hu, Yibao Wei, Taiyang Liao, Deren Liu, Zijian Gong, Jun Mao, Peimin Wang, Nongshan Zhang   +7 more
wiley   +1 more source