Association Between Migraine and Periodontitis: A Systematic Review and Meta‐Analysis
European Journal of Neurology, Volume 32, Issue 10, October 2025.People exposed to migraine are 1.8 times more likely to develop periodontitis. This fact highlights the role of oral diseases that have an inflammatory component in the patient's general health affecting quality of life. Preventing periodontitis in the initial stages could contribute to the reduction of local and systemic inflammation.
Gabriel Bernat Camps‐Plomer +3 more
wiley +1 more source
Tonic inhibitory control exerted by opioid peptides in the paraventricular nuclei of the hypothalamus on regional hemodynamic activity in rats [PDF]
, 2002 Andrée Lessard, Hélène Bachelard
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Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.ABSTRACT While RTP4 is known to regulate odorant receptor trafficking, its role in colorectal cancer (CRC) remains unclear. This study investigates the clinical relevance and functional mechanisms of RTP4 in CRC. Comprehensive analyses revealed significant downregulation of RTP4 expression in CRC tissues, correlating with poor patient prognosis.
Chengpeng Yu +7 more
wiley +1 more source
Astrocytes as Active Participants in Memory
Journal of Neurochemistry, Volume 169, Issue 10, October 2025.This review explores how astrocytes support memory by modulating neurotransmitters, interacting with biomolecules, and taking part in synaptic plasticity. We discuss their role across various brain regions and spotlight cutting‐edge methods—such as Ca2+ imaging, optogenetics, chemogenetics, and engram analysis—that have revolutionized our ability to ...
Shay Meron Asher, Inbal Goshen
wiley +1 more source
Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain [PDF]
, 2003 Victor J. Hruby +7 more
openalex +1 more source
Comparative drugability evaluation of MOR opioid peptides in functional brain research [PDF]
, 2010 Adriaens, Antita +6 more
core
Journal of Neuroendocrinology, Volume 37, Issue 10, October 2025.Abstract We aimed to assess the symptoms and impact on overall survival (OS) from bone metastases (BM) diagnosed on Gallium‐68‐labelled DOTA tyrosine octreotide positron emission tomography with computed tomography (68Ga‐DOTATOC‐PET/CT) in patients with well‐differentiated small intestinal neuroendocrine tumours (Si‐NETs).
Maria Wedin +4 more
wiley +1 more source
The pharmacotherapeutic potential of neuropeptide Y for chronic pain
Journal of Internal Medicine, Volume 298, Issue 4, Page 280-296, October 2025.Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
wiley +1 more source
Orphanin FQ/nociceptin: an endogenous peptide agonist for the orphan opioid receptor
, 1998 David G. Lambert, David K. Grandy
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Colloquium C10: Opioid Peptides: Normal & Pathologic Signaling Mechanisms in Neurons & Glia [PDF]
, 2003 openalex +1 more source