Results 21 to 30 of about 21,347 (246)
Archives of Forensic Medicine and Criminology, 2015 The aim of the paper is to discuss the role of respiratory failure caused by endogenous (both structural and functional) abnormalities in the central nervous system and exogenous food-derived opioid-like peptides in the pathogenesis of sudden infant ...
Barbara Sumińska-Ziemann +2 more
doaj +1 more source
Opioid Receptors in Immune and Glial Cells—Implications for Pain Control
Frontiers in Immunology, 2020 Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Halina Machelska, Melih Ö. Celik
doaj +1 more source
Opioid Peptides: Pharmaceutical Significance and Formulation Approaches
, 2023 Opioids have been used in pain management for thousands of years due to the pain relief effects that they show by binding to their own receptors. Nowadays, their use continues in a more controlled manner because they have various side effects and a ...
Selin Seda TİMUR +7 more
core +1 more source
Bioactive peptides in storage proteins
Grasas y Aceites, 2000 A review on the bioactive peptides described so far in storage proteins, mainly milk proteins, has been carried out. Bioactive peptides are small amino acid sequences inactives in the native protein, but that can be liberated after hydrolysis of these ...
J. Vioque +5 more
doaj +1 more source
Diabetology & Metabolic Syndrome, 2021 Background Prediabetes is characterized by a hemoglobin A1c of 5.7–6.4% and fasting blood glucose of 100–125 mg/dl. A high percentage of prediabetes subjects develop type 2 diabetes mellitus in the next years.
Shatha Rouf Moustafa
doaj +1 more source
Opioid peptides encrypted in intact milk protein sequences [PDF]
, 2000 Opioid agonistic and antagonistic peptides which are inactive within the sequence of the precursor milk proteins can be released and thus activated by enzymatic proteolysis, for example during gastrointestinal digestion or during food processing ...
Meisel, Hans +2 more
core +1 more source
Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions
Frontiers in Pharmacology, 2013 Mechanisms of endogenous pain control are significant. Increasing studies have clearly produced evidence for the clinical usefulness of opioids in peripheral analgesia.
Katerina eIwaszkiewicz +2 more
doaj +1 more source
eLife, 2021 Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstream ...
Jennifer M Kunselman +4 more
doaj +1 more source
Endogenous peripheral pain regulatory systems in orofacial pain patients
Saudi Dental Journal, 2019 Introduction: Initiation of pulpal pain begins with the release of bacterial toxins and inflammatory mediators that either activate or sensitize nociceptors thereby activating the trigeminal pain pathway.
Abdulmajeed M. Al Shujaa +4 more
doaj +1 more source
Molecular Pain, 2014 Background: Leukocytes containing opioid peptides locally control inflammatory pain. In the early phase of complete Freund's adjuvant (CFA)-induced hind paw inflammation, formyl peptides (derived e.g. from Mycobacterium butyricum ) trigger the release of
Reine-Solange Sauer +8 more
doaj +1 more source