BIOME cohort: Multi‐system microbiome dynamics and clinical outcomes in massive burn injury patients
Massive burn injuries (MBIs) are associated with high mortality and disability rates, primarily due to microbial‐driven sepsis from extensive skin barrier loss and subsequent scar formation. This makes MBI a compelling model for studying multi‐system microbial dysbiosis following skin barrier destruction.
Runzhi Huang +72 more
wiley +1 more source
Phosphorylation of the δ-Opioid Receptor Regulates Its β-Arrestins Selectivity and Subsequent Receptor Internalization and Adenylyl Cyclase Desensitization [PDF]
Yu Qiu, Horace H. Loh, Ping‐Yee Law
openalex +1 more source
Understanding Substance Use and Suicide Risk Among LGBTQ+ College Students Post‐COVID‐19
ABSTRACT This study examines the reported frequency of substance use, levels of suicide risk, and their relationships among LGBTQ+ college students (N = 192) following the COVID‐19 pandemic. Participants most commonly reported alcohol and marijuana use, and least commonly reported unprescribed prescription opioid or heroin use.
Afroze N. Shaikh +6 more
wiley +1 more source
Major Depressive Disorder and Kappa Opioid Receptor [PDF]
Wei Li +7 more
openalex +1 more source
Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance [PDF]
Hisakatsu Ito +17 more
openalex +1 more source
Integrating the Gestalt Model of Self With Psychedelic‐Assisted Psychotherapy
ABSTRACT This theoretical integration paper employs a conceptual analysis methodology to synthesize the Gestalt model of self‐as‐process with Psychedelic Somatic Interactional Psychotherapy (PSIP). Unlike traditional psychedelic therapy models that defer therapeutic engagement to postsession integration, PSIP emphasizes an active, directive therapeutic
Travis R. Fox
wiley +1 more source
Exploring the roles and impacts of pharmacists embedded in general practice: a scoping review
Abstract Background The role of the general practice pharmacist (GPP) in Australia is not yet clearly defined, and their clinical expertise remains underutilised in general practice settings. This may be attributed to a limited understanding of pharmacists' capabilities, which can hinder optimal GPP utilisation.
Christel Chandra +3 more
wiley +1 more source
Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake
Daniel W. Bloodgood +9 more
openalex +2 more sources

