Results 51 to 60 of about 81,908 (215)

Deletion of arrestin-3 does not reduce drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration

Frontiers in Pharmacology
IntroductionOpioid drugs are potent analgesics that mimic the endogenous opioid peptides, endorphins and enkephalins, by activating the µ-opioid receptor.
Sarah Warren Gooding, Lindsey Felth, Randi Foxall, Zachary Rosa, Kyle Ireton, Izabella Sall, Joshua Gipoor, Anirudh Gaur, Madeline King, Noah Dirks, Cheryl Allyne Whistler, Jennifer Lynne Whistler, Jennifer Lynne Whistler   +12 more
doaj   +1 more source

Influence of the hypothalamic arcuate nucleus on intraocular pressure and the role of opioid peptides.

PLoS ONE, 2014
BackgroundAn opioid peptide neuron/humoral feedback regulation might be involved in changes of intraocular pressure (IOP). The aims of this study are to investigate the effects of arcuate nucleus (ARC) and opioid peptides on intraocular pressure (IOP ...
Ji Jin, Guo-xu Xu, Zhi-lan Yuan
doaj   +1 more source

Endogenous opioids regulate moment-to-moment neuronal communication and excitability

Nature Communications, 2017
The endogenous opioid system regulates fear and anxiety, but the underlying cellular mechanism is unclear. Winterset al. shows that in the intercalated cells (ITC) of the amygdala, endogenous opioids suppress glutamatergic inputs via the δ-opioid ...
Bryony L. Winters, Gabrielle C. Gregoriou, Sarah A. Kissiwaa, Oliver A. Wells, Danashi I. Medagoda, Sam M. Hermes, Neil T. Burford, Andrew Alt, Sue A. Aicher, Elena E. Bagley   +9 more
doaj   +1 more source

Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase

Nature Communications, 2017
Opioid receptors are important modulators of nociceptive pain. Here the authors show that opioid receptor activation recruits peroxiredoxin 6 (PRDX6) to the receptor-Gαi complex by c-Jun N-terminal kinase, resulting in Gαi depalmitoylation and enhanced ...
Selena S. Schattauer, Benjamin B. Land, Kathryn L. Reichard, Antony D. Abraham, Lauren M. Burgeno, Jamie R. Kuhar, Paul E. M. Phillips, Shao En Ong, Charles Chavkin   +8 more
doaj   +1 more source

Characterization of opioid receptors in the cat carotid body involved in chemosensory depression in vivo [PDF]

, 1986
Geoffrey C. Kirby, Daniel S. McQueen
openalex   +1 more source

Central Injection of Endomorphin-2, but not Endomorphin-1, Increases Food Intake in Chicks via μ1-opioid Receptors

The Journal of Poultry Science, 2007
The endogenous tetrapeptides endomorphin-1 and -2 are potent, selective μ-opioid receptor agonists in mammals. The present study was done to elucidate whether central injection of endomorphins enhances feeding behavior in chicks, and to investigate ...
Takashi Bungo, Koh-Ichi Dodo, Tomofumi Izumi   +2 more
doaj   +1 more source

Monoclonal antibody to the message sequence Tyr-Gly-Gly-Phe of opioid peptides exhibits the specificity requirements of mammalian opioid receptors. [PDF]

, 1983
T Meo, C. Gramsch, R Inan, V. Höllt, E Weber, A. Herz, G. Riethmüller   +6 more
openalex   +1 more source

Differential ontogeny of multiple opioid receptors (mu, delta, and kappa) [PDF]

, 1985
J W Spain, BL Roth, CJ Coscia
openalex   +1 more source

Opioids increase potassium conductance in submucous neurones of guinea‐pig caecum by activating δ‐receptors [PDF]

, 1986
S. Mihara, R. Alan North
openalex   +1 more source

In-vivo studies on kappa opioid receptors [PDF]

, 1986
Alan Cowan, Debra E. Gmerek
openalex   +1 more source