Results 151 to 160 of about 130,157 (357)
Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne
In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku+3 more
wiley +1 more source
Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke+4 more
wiley +1 more source
Clinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer
Cardiac wasting‐associated cardiomyopathy in cancer patients. E/e', early diastolic filling velocity (E) over mitral annulus early diastolic tissue velocity (e'); GLS, global longitudinal strain; LV, left ventricular; LVEF, left ventricular ejection fraction; TAPSE, tricuspid annular plane systolic excursion.
Markus S. Anker+27 more
wiley +1 more source
Buprenorphine in Neonatal Abstinence Syndrome. [PDF]
Infants exposed in utero to opioids will demonstrate a withdrawal syndrome known as neonatal abstinence syndrome (NAS). Buprenorphine is a long-acting opioid with therapeutic use in medication-assisted treatment of opioid dependency in adults and ...
Kraft, Walter K.
core +1 more source
Intramolecular Heck Reactions of Cyclic Sulfonamides: Regiochemical Trends and Reductive Cleavage
The synthesis of a new class of cyclic sulfonamides and their subsequent conversion into substituted N‐heterocycles is reported. Methyl‐substituted tetrahydropyridine and tetrahydro‐azepine Heck precursors are prepared and cyclized to provide a variety of regioisomeric products.
Hanno Stanley+3 more
wiley +1 more source
The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature. [PDF]
Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal ...
Baratta, Jaime L.+5 more
core +1 more source
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont+2 more
wiley +1 more source
Intrathecal Pertussis Toxin Treatment Attenuates Opioid Antinociception and Reduces High-affinity State of Opioid Receptors [PDF]
Chih‐Shung Wong+3 more
openalex +1 more source