Results 181 to 190 of about 2,576,885 (397)

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

British Journal of Clinical Pharmacology, EarlyView.
Jakša Vukojević, Luka Horvat, Vito Papić, Andrija Štajduhar   +3 more
wiley   +1 more source

Effects of Long‐Term Exposure to the Earned Income Tax Credit on Work Disability in Later Life

Health Economics, EarlyView.
ABSTRACT This study investigates the impact of the Earned Income Tax Credit (EITC) on work disability and Social Security Disability Insurance (DI) claims among Americans. Utilizing the Panel Study of Income Dynamics, we examine the effects of EITC exposure from birth to mid‐adulthood on work disability risk before retirement. Our analysis reveals that
Katie Jajtner, Keisha T. Solomon, Yang Wang   +2 more
wiley   +1 more source

Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice

, 2018
Keith M. Olson, Attila Keresztes, Jenna Tashiro, Lisa V. Daconta, Victor J. Hruby, John M. Streicher   +5 more
openalex   +1 more source

Targeting multiple opioid receptors – improved analgesics with reduced side effects?

British Journal of Pharmacology, 2018
T. Günther, Pooja Dasgupta, Anika Mann, E. Miess, A. Kliewer, S. Fritzwanker, Ralph Steinborn, S. Schulz   +7 more
semanticscholar   +1 more source

Biomarkers of morphine tolerance and dependence are prevented by morphine‐induced endocytosis of a mutant μ‐opioid receptor

, 2009
He Li, Joseph A. Kim, Jennifer L. Whistler   +2 more
openalex   +1 more source

Presence and Location of CatSper 1–4, Opioid (μ, δ and κ) and CD44 Receptors in Spermatozoa from Aoudad, Iberian Ibex and Mouflon

Veterinary Medicine and Science
Despite the apparent progress in reproductive technologies in wild ruminant species, healthy live births have been limited. Acquiring a sound knowledge of the molecular basis of most functional aspects of spermatozoa will improve the effectiveness of ...
Alejandro Vicente‐Carrillo, Manuel Álvarez‐Rodríguez, Cristina Castaño, Adolfo Toledano‐Díaz, Eva Martínez‐Nevado, Heriberto Rodríguez‐Martínez, Julián Santiago‐Moreno   +6 more
doaj   +1 more source

Allostery at opioid receptors: modulation with small molecule ligands

British Journal of Pharmacology, 2018
Kathryn E. Livingston, J. Traynor
semanticscholar   +1 more source

Spirocyclic Diamine Scaffolds for Medicinal Chemistry

Helvetica Chimica Acta, EarlyView.
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel, Alejandro Flores, Maedeh Darsaraee, Jean‐Louis Reymond   +3 more
wiley   +1 more source

Author response for "Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats"

, 2021
Megan A. Johnson, Natalina H. Contoreggi, Joshua F. Kogan, Matthew Bryson, Batsheva R. Rubin, Jason D. Gray, Mary Jeanne Kreek, Bruce S. McEwen, Teresa A. Milner   +8 more
openalex   +1 more source

Insights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance.

Handbook of Experimental Pharmacology, 2017
J. Galligan, C. Sternini
semanticscholar   +1 more source