Results 41 to 50 of about 120,543 (256)

Effect of police action on low-barrier substance use disorder service utilization

open access: yesHarm Reduction Journal, 2022
Background Police action can increase risky substance use patterns by people who use drugs (PWUD), but it is not known how increased police presence affects utilization of low-barrier substance use disorder bridge clinics.
Karrin Weisenthal   +5 more
doaj   +1 more source

Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. [PDF]

open access: yes, 2020
Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the ...
Carrette, Lieselot LG   +7 more
core  

Association between recent overdose and chronic pain among individuals in treatment for opioid use disorder.

open access: yesPLoS ONE, 2022
Chronic pain increases risk for opioid overdose among individuals with opioid use disorder. The purpose of this study is to evaluate the relationship between recent overdose and whether or not chronic pain is active.
Sarah M Hartz   +8 more
doaj   +2 more sources

Primary care management of Long-Term opioid therapy

open access: yesAnnals of Medicine, 2022
The United States underwent massive expansion in opioid prescribing from 1990–2010, followed by opioid stewardship initiatives and reduced prescribing.
Phillip O. Coffin   +3 more
doaj   +1 more source

Immunopharmacotherapies for Treating Opioid Use Disorder [PDF]

open access: yesTrends in Pharmacological Sciences, 2018
The current opioid crisis has reinvigorated interest in the development of therapeutics for opioid use disorder (OUD), and the choice of preclinical translational endpoints is an essential consideration. Antiopioid immunopharmacotherapies (e.g., conjugate vaccines) that sequester drug peripherally, preventing opioids from reaching targeted receptors in
Matthew L. Banks   +2 more
openaire   +3 more sources

Multidimensional Recovery Among an Opioid Use Disorder Outpatient Treatment Population [PDF]

open access: yes, 2020
Background: Given the current opioid crisis, recovery from opioid use disorder (OUD) warrants attention. SAMHSA’s working definition of recovery highlights dimensions that support recovery including health, home, community, and purpose.
Beck, Lori   +2 more
core   +1 more source

Spatial Concentration of Opioid Overdose Deaths in Indianapolis: An Application of the Law of Crime Concentration at Place to a Public Health Epidemic [PDF]

open access: yes, 2019
The law of crime concentration at place has become a criminological axiom and the foundation for one of the strongest evidence-based policing strategies to date.
Carter, Jeremy G.   +2 more
core   +1 more source

Pharmacogenetics of Opioid Use Disorder Treatment [PDF]

open access: yesCNS Drugs, 2018
Opioid use disorder (OUD) is a significant health problem in the United States and many other countries. A combination of issues, most notably increased prescription of opioid analgesics, has resulted in climbing rates of opioid abuse and overdose over the last decade.
Richard C. Crist   +2 more
openaire   +2 more sources

The molecular neurobiology and neuropathology of opioid use disorder

open access: yesCurrent Research in Neurobiology, 2021
The number of people diagnosed with opioid use disorder has skyrocketed as a consequence of the opioid epidemic and the increased prescribing of opioid drugs for chronic pain relief. Opioid use disorder is characterized by loss of control of drug taking,
Christopher A. Blackwood, Jean Lud Cadet
doaj  

Promoting Awareness of the Opioid Epidemic in Rural Vermont [PDF]

open access: yes, 2017
Vermont is in the middle of an opioid epidemic. Heroin use fatalities are on the rise and the number of people in treatment for opioid use disorder in Rutland County has tripled in recent years.
Olson, Kathleen
core   +1 more source

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