Results 121 to 130 of about 45,788 (261)

Probable cychlorphine exposure in a patient with opioid use disorder: A case report

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Cychlorphine is an emerging synthetic opioid with limited clinical data. Methods We describe a patient's reported cychlorphine use and its's clinical effects. Results Thirty‐five years old male with opioid use disorder reported purchasing cychlorphine online.
Manroop Bal   +4 more
wiley   +1 more source

Targeting mitochondrial dynamics of morphine-responsive dopaminergic neurons ameliorates opiate withdrawal

open access: yesThe Journal of Clinical Investigation
Converging studies demonstrate the dysfunction of the dopaminergic neurons following chronic opioid administration. However, the therapeutic strategies targeting opioid-responsive dopaminergic ensembles that contribute to the development of opioid ...
Changyou Jiang   +6 more
doaj   +1 more source

Opioid Prescribing Changes in Advanced Cancer Before and After Withdrawal of Hydromorphone Slow‐Release Tablets

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Hydromorphone slow‐release tablet withdrawal from the Australian market altered opioid prescribing patterns in advanced cancer pain. Methadone use increased by nearly 50% and median doses doubled. There may be a need to tailor clinician training on safe and effective use of methadone and other opioids as appropriate. ABSTRACT Aim Ongoing disruptions to
Aaron K. Wong   +7 more
wiley   +1 more source

Novel pharmacotherapies for opioid use disorder and opioid withdrawal. [PDF]

open access: yesFront Psychiatry
Shen MR   +6 more
europepmc   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres   +19 more
wiley   +1 more source

Project for Universal Management of Airways: guidelines for tracheal extubation

open access: yesAnaesthesia, EarlyView.
Summary Introduction Risk evaluation, strategy formulation and preparation are important to decreasing the incidence of adverse events associated with tracheal extubation. The focus of this guideline is tracheal extubation, but many of the principles outlined are relevant to all forms of discontinuation of airway management (tracheal extubation ...
Louise Ellard   +14 more
wiley   +1 more source

Association of pre‐operative opioid use disorder and postoperative outcomes: a systematic review and meta‐analysis

open access: yesAnaesthesia, EarlyView.
Summary Introduction Opioid use disorder may increase the risk of adverse postoperative outcomes, but the magnitude and consistency of this association remain unclear. We performed a systematic review and meta‐analysis to evaluate the impact of opioid use disorder on postoperative outcomes across surgical populations.
Dereje Zewdu Assefa   +4 more
wiley   +1 more source

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