Results 191 to 200 of about 45,788 (261)

The acute and chronic effects of local aerobic exercise on cardiovascular physiology

Experimental Physiology, EarlyView.
Abstract Exercise training has beneficial effects for primary and secondary prevention of cardiovascular disease (CVD). Effects of exercise training have typically been studied in the form of whole‐body exercise training, partly driven by the assumption that larger effects of exercise training can be achieved by involving more and larger muscle groups.
Myrthe P. F. van de Ven, Janneke Vloet, Daphne Merkus, Dick H. J. Thijssen   +3 more
wiley   +1 more source

Effects of suvorexant on diurnal cortisol and patient-reported stress during opioid withdrawal in a randomized trial. [PDF]

Psychoneuroendocrinology
McKendrick G, Clapham C, Zipunnikov V, Ellis JD, Finan P, Dunn KE, Strain EC, Wolinsky D, Huhn AS.   +8 more
europepmc   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

The Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Psychosis-like symptoms and seizure in a case of complicated opioid withdrawal from heroin use. [PDF]

Ind Psychiatry J
Malik I, Khanra S, Mukherjee A, Munda SK.   +3 more
europepmc   +1 more source

Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia and no‐pain controls completed questionnaire ratings of chronic pain, childhood trauma, anxiety and depression. During the first session a conditioned pain modulation task was administered, with heat pain applied via thermode and cold pain via cold water‐bath.
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Emrys Jones, Jeffery Lewis, Sandy R. Hu, Nathaniel Schuster, Laura Case   +9 more
wiley   +1 more source

Brief report: Opioid withdrawal in patients with cirrhosis: A retrospective cross-sectional United States analysis. [PDF]

Am J Addict
Behrend C, Ferreira AD, Goble SR.
europepmc   +1 more source

TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain‐like behaviors in rats with neuropathic pain

The Journal of Physiology, EarlyView.
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez, Kimberly Gomez, Alessandro Porro, Gerhard Thiel, Anna Moroni, Heather N. Allen, Rajesh Khanna, Andrea Saponaro   +7 more
wiley   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Ketamine in treating opioid use disorder and opioid withdrawal: a scoping review. [PDF]

Front Psychiatry
Shen MR, Campbell DE, Kopczynski A, Maddams S, Rosenblum N, Nigam K, Suzuki J.   +6 more
europepmc   +1 more source

Association of Propofol Versus Midazolam Sedation With Successful Pharyngeal Observation During Upper Gastrointestinal Endoscopy: A Retrospective Study

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Adequate pharyngeal observation during esophagogastroduodenoscopy (EGD) is increasingly recognized as an important component of high‐quality upper gastrointestinal endoscopy. However, visualization may be impaired by gag reflexes and patient movement.
Kazuya Sumi, Tomoya Sato, Tomona Sakurai, Kota Uehara, Akira Ishihara, Takayoshi Ito   +5 more
wiley   +1 more source