Results 1 to 10 of about 410,058 (309)

VER-01 Shows Enhanced Gastrointestinal Tolerability, Superior Pain Relief, and Improved Sleep Quality Compared to Opioids in Treating Chronic Low Back Pain: A Randomized Phase 3 Clinical Trial [PDF]

open access: yesPain and Therapy
Introduction Chronic low back pain (CLBP) affects over half a billion people worldwide. Current pharmacologic treatments, comprising mainly non-steroidal anti-inflammatory drugs and opioids, offer limited efficacy and pose significant risks, warranting ...
Winfried Meissner   +4 more
doaj   +2 more sources

First drug-checking study at an electronic festival and fentanyl detection in the central region of Mexico

open access: yesHarm Reduction Journal, 2023
Background Perception of drug adulteration has increased in Mexico, but there is little research on adulterants and toxicity. The aim of this study was to identify drug composition in an electronic music outdoor festival nearby Mexico City.
Silvia L. Cruz   +4 more
doaj   +1 more source

Analysis of Opioid-Related Adverse Events in Japan Using FAERS Database

open access: yesPharmaceuticals, 2023
Adverse events associated with opioid use in palliative care have been extensively studied. However, predicting the occurrence of adverse events based on the specific opioid used remains difficult.
Risako Hirai, Yoshihiro Uesawa
doaj   +1 more source

Unspecified opioids among opioid overdoses in Oslo, Norway

open access: yesBMC Research Notes, 2022
Objective Since 2017, an increasing number of opioid overdoses in Oslo, Norway, has been categorized as involving unspecified opioids, as noted in the patient records by the doctor treating the patient.
Zahra Zeineb Iqbal   +3 more
doaj   +1 more source

Risk Factors Associated with Prolonged Postoperative Opioids Use in Non-Cancer Patients Undergoing Spinal Surgery: a Retrospective Study

open access: yesJournal of Health Science and Medical Research (JHSMR), 2022
Objective: To identify risk factors associated with prolonged postoperative opioids use in non-cancer patients undergoing spinal surgery. Material and Methods: The medical records of patients, who underwent spinal surgery at Songklanagarind Hospital ...
Arpawan Thepsuwan   +2 more
doaj   +1 more source

Opioid-related polysubstance use and its effect on mortality and health resource utilization among trauma patients

open access: yesInjury Epidemiology, 2023
Background Pre-injury opioid use is common, but the effects of opioid-related polysubstance use on mortality and health resources utilization (HRU) have not been investigated yet.
Safalta Khadka   +2 more
doaj   +1 more source

Maternal opioids age-dependently impair neonatal respiratory control networks

open access: yesFrontiers in Physiology, 2023
Infants exposed to opioids in utero are an increasing clinical population and these infants are often diagnosed with Neonatal Abstinence Syndrome (NAS). Infants with NAS have diverse negative health consequences, including respiratory distress.
Sarah A. Beyeler   +6 more
doaj   +1 more source

Relation between opioid consumption and inclusion of opioids in 137 national essential medicines lists

open access: yesBMJ Global Health, 2020
Introduction Opioids are deemed essential medicines by the World Health Organization (WHO). However, many countries have inadequate access to them.
Carl Heneghan   +5 more
doaj   +1 more source

Trends in opioid prescribing practices in South Korea, 2009-2019: Are we safe from an opioid epidemic?

open access: yesPLoS ONE, 2021
Opioid prescribing data can guide regulation policy by informing trends and types of opioids prescribed and geographic variations. In South Korea, the nationwide data on prescribing opioids remain unclear.
Noo Ree Cho   +5 more
doaj   +1 more source

Maternal Methadone Destabilizes Neonatal Breathing and Desensitizes Neonates to Opioid-Induced Respiratory Frequency Depression

open access: yesFrontiers in Physiology, 2021
Pregnant women and developing infants are understudied populations in the opioid crisis, despite the rise in opioid use during pregnancy. Maternal opioid use results in diverse negative outcomes for the fetus/newborn, including death; however, the ...
Austin D. Hocker   +3 more
doaj   +1 more source

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