Results 141 to 150 of about 315,380 (361)

Opioids and cancer survival: are we looking in the wrong place?

open access: yesBJA Open, 2022
There is a controversial narrative in the anaesthetic literature suggesting that anaesthetic technique (including opioids) may be detrimental to survival after tumour resection. The initial observations were retrospective. Several prospective studies are
Despina Giakomidi   +2 more
doaj  

Antinociceptive and Anti‐inflammatory Effect of Nicandrin B Isolated From Datura ferox in Zebrafish

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects in adult zebrafish (Danio rerio). Animals treated with Nic B (4, 20, and 40 mg/kg) showed no toxicity and maintained normal locomotor activity.
Jéssica Bezerra Maciel   +15 more
wiley   +1 more source

Litigation-Ending Sanctions: Alaska Courts’ Use of Rule 37 [PDF]

open access: yes, 1985
Pain is a common symptom of a number of conditions including cancer and one of the most frequent reasons for seeking healthcare. Acute and chronic pain result in considerable discomfort with a detrimental impact on the quality of life.
Carroll, Robert
core   +1 more source

Speaking of Stigma: Piloting Language Training in Addiction Counseling Coursework

open access: yesCounselor Education and Supervision, EarlyView.
ABSTRACT This pilot study examined counselor‐in‐training (CIT) attitudes and awareness regarding stigma and stigmatizing language aimed at those with substance use disorders before and after an author‐developed educational intervention. Results indicated this intervention positively impacted CIT awareness and attitudes and their ability to identify and
Amy L. Grybush   +2 more
wiley   +1 more source

Sustainable Approaches for the Protection and Deprotection of Functional Groups

open access: yesChemistry – A European Journal, EarlyView.
Shield: Protection and deprotection are key to selective synthesis, but conventional methods can lack sustainability. This review highlights electrochemical and photochemical strategies as greener alternatives, emphasizing their mechanisms, functional group tolerance, and broad synthetic utility.
Ju Ha Jin   +5 more
wiley   +1 more source

Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities

open access: yesChemMedChem, EarlyView.
Continuous flow technology is exploited for the generation of bicyclic pyrazolines via photo‐click reactions. These heterocyclic species contain a valuable 3D scaffold along with a polar succinimide moiety. Subsequent antimicrobial testing reveals that halogenated moieties such as chlorine atoms and trifluoromethoxy groups enhance the potency of these ...
Debora Caviglia   +4 more
wiley   +1 more source

Opioid-mediated suppression of interferon-gamma production by cultured peripheral blood mononuclear cells. [PDF]

open access: bronze, 1987
Phillip K. Peterson   +4 more
openalex   +1 more source

Editorial: Opioids and opioid-use disorders

open access: yesFrontiers in Pharmacology, 2023
Giordano de Guglielmo   +5 more
openaire   +4 more sources

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