Results 271 to 280 of about 315,380 (361)

Concurrent Prescribing of Opioids and Sedative-Hypnotic Drugs for Long-Term Use in Australian General Practice: A Cross-Sectional Analysis Using MedicineInsight. [PDF]

Pharmacol Res Perspect
Williams S, Rositano J, Haeusler C, Bhat M, Omond K, Stocks N, Gonzalez-Chica D.   +6 more
europepmc   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Opioid analgesics: Managing the predictable. [PDF]

Clin Med (Lond)
Barnes A, Heppenstall-Harris G, Dickman A.   +2 more
europepmc   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

Pharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations. [PDF]

Pharmacotherapy
Shendre A, Liu X, Chiang C, Goodwin A, Oteng SR, Deypalubos JAF, Zhang S, Wang L, Liu J, Abbasi MY, Aruldhas BW, Zaidi SS, Kirkpatrick LM, Silva LD, Overholser BR, O'Kane AM, Kannankeril PJ, Patrick SW, Wiese AD, Quinney SK, Li L.   +20 more
europepmc   +1 more source

Restless Legs Syndrome and Impulsive Decision‐Making: Impact of Symptom Severity, Chronotype and Interoception

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Restless Legs Syndrome (RLS) is a neurological disorder reported to be associated with impulsivity and impairments in interoception and emotional regulation. However, limited research has explored the combined influence of RLS severity, psychological factors, and chronotype on impulsive decision‐making and risk‐taking behavior in ...
Giacomo Carollo, Riccardo Quinci, Gloria Pompea Mingolla, Angela Sandri, Michele Tinazzi, Elena Antelmi   +5 more
wiley   +1 more source

Mending the divide: integrating opioid analgesia and immunotherapy for optimal cancer care. [PDF]

J Immunother Cancer
DeJohn C, Zsiros E.
europepmc   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Opioids, Addiction Treatment, and the Long Tail of Eugenics [PDF]

, 2019
Appleman, Laura I.
core  

Associations between klotho levels and mortality risk among middle-aged and older adults taking prescription opioids. [PDF]

Prev Med Rep
Liu C, Hu J, Zhou R, Zhu J, Mao H.
europepmc   +1 more source