Results 51 to 60 of about 469,418 (405)

Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer

Cancer Medicine, Volume 11, Issue 24, Page 5001-5012, December 2022., 2022
Nerve invasion (N‐inv) is an important prognostic factor in pancreatic ductal adenocarcinoma (PDAC). To elucidate circulating stimulators for nerve invasion, the authors evaluated the stimulant activity and the inhibitory effects of IL‐6/gp130 axis. Biological activity of IL‐6/gp130 axis promoted nerve invasion in murine model and was upregulated in ...
Hidetaka Suzuki, Shuichi Mitsunaga, Masafumi Ikeda, Takao Aoyama, Kazumi Yoshizawa, Masayuki Yamaguchi, Masami Suzuki, Minoru Narita, Toshikatsu Kawasaki, Atsushi Ochiai   +9 more
wiley   +1 more source

Attitudes of Black American Christian church leaders toward Opioid Use Disorder, overdoses, and harm reduction: a qualitative study

Frontiers in Psychiatry
IntroductionBlack American Christian church leaders are trusted community members and can be invaluable leaders and planners, listeners, and counselors for Opioid Use Disorder (OUD) sufferers in the opioid overdose crisis disproportionately affecting the
Akosua B. Dankwah, Richard B. Siegrist, Ira B. Wilson, Ira B. Wilson, Michelle McKenzie, Michelle McKenzie, Josiah D. Rich, Josiah D. Rich   +7 more
doaj   +1 more source

Profile of drug users in the residential treatment centers of Tehran, Iran [PDF]

Health Promotion Perspectives, 2019
Background: The current study aimed at determining the pattern of drug dependence and its related factors in mid-term residential treatment centers (MTRCs). Methods: The current cross-sectional study was conducted on all drug dependent people residing in
Hossein Akbari, Mohsen Roshanpajouh, Keramat Nourijelyani, Mohammad-Ali Mansournia, Afarin Rahimi-Movaghar, Kamran Yazdani   +5 more
doaj   +1 more source

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? [PDF]

, 2015
© 2015, BMJ Publishing Group. All rights reserved. Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this
Currow, David C., Ekstrom, Magnus, Ekström, Magnus, Johnson, Miriam J., Kaasa, S., Kaasa, Stein, Klepstad, Pal, Klepstad, Päl, Quinn, S., Quinn, Stephen, Somogyi, Andrew A.   +10 more
core   +1 more source

Dose of intra‐operative opioids has no impact on recurrence or survival in primary liver cancer

Cancer Medicine, Volume 11, Issue 24, Page 4927-4934, December 2022., 2022
Kaplan‐meier curves for recurrence‐free and overall survial of high‐dose and low‐dose groups. No significant difference in recurrence‐free survial (A) or overall survial (B) after surgery was noted when comparing high‐dose with low‐dose groups. Abstract Background Intra‐operative use of opioid analgesics might have an impact on cancer recurrence and ...
Liuyuan Zhao, Lei Teng, Wenhui Zhang, Shiyan Lin, Xuejiao Liu, Junzhu Dai, Hongxue Shao, Xiaoshi Li, Quan Liu, Huichao Zou   +9 more
wiley   +1 more source

Concomitant benzodiazepine and opioids decrease sleep apnoea risk in chronic pain patients

ERJ Open Research, 2020
Background The concurrent use of sedating centrally acting drugs and opioids by chronic pain patients occurs routinely despite concerns of negative impacts on respiration during sleep.
Soodaba Mir, Jean Wong, Clodagh M. Ryan, Geoff Bellingham, Mandeep Singh, Rida Waseem, Danny J. Eckert, Frances Chung   +7 more
doaj   +1 more source

The Society for Pediatric Anesthesia recommendations for the use of opioids in children during the perioperative period

Paediatric anaesthesia, 2019
Opioids have long held a prominent role in the management of perioperative pain in adults and children. Published reports concerning the appropriate, and inappropriate, use of these medications in pediatric patients have appeared in various publications ...
J. Cravero, R. Agarwal, C. Berde, P. Birmingham, C. Coté, J. Galinkin, L. Isaac, S. Kost‐Byerly, D. Krodel, L. Maxwell, T. Voepel-Lewis, N. Sethna, R. Wilder   +12 more
semanticscholar   +1 more source

Comparison of opioid prescribing by dentists in the United States and England [PDF]

, 2019
Importance: The United States consumes most of the opioids worldwide despite representing a small portion of the world\u27s population. Dentists are one of the most frequent US prescribers of opioids despite data suggesting that nonopioid analgesics are ...
Calip, Gregory S, Durkin, Michael J, Gellad, Walid F, Kim, Hajwa, Lockhart, Peter B, Rowan, Susan A, Suda, Katie J, Thornhill, Martin H   +7 more
core   +1 more source

A primary care, multi-disciplinary disease management program for opioid-treated patients with chronic non-cancer pain and a high burden of psychiatric comorbidity [PDF]

, 2005
BACKGROUND: Chronic non-cancer pain is a common problem that is often accompanied by psychiatric comorbidity and disability. The effectiveness of a multi-disciplinary pain management program was tested in a 3 month before and after trial.
A Rosenblum, AK Burton, AM Elliott, B McCarberg, B Meier, C Maier, CA Hammett-Stabler, CA Soderstrom, CD DeAngelis, CS Cleeland, CS Cleland, CS Cleland, D Bloodsworth, D Fujimoto, DA Fishbain, DA Regier, Darren A DeWalt, DC Turk, DC Turk, DE Joranson, DE Joranson, DE Moulin, DE Weissman, DG Rischitelli, DJ Kavanagh, H Flor, H Ghodse, H McQuay, J Gardner-Nix, J Porter, J Stephen Perhac, JD Bartleson, JD Clark, JE Veney, JK Iglehart, JM Harris Jr, JM Romano, JT Chibnall, JT Farrar, Katherine M Felix, KB Wells, L Allan, L Peters, L Radloff, L Webb, LH Pengel, LK Mannix, M van Tulder, Mary E Bryant, MC Reid, MC Rowbotham, ME Geisser, MF Ballesteros, MI Donovan, Michael P Pignone, MJ Bair, MJ Bair, NG Hoffmann, NJ Adams, OxyContin®, P Belluck, PA Hill, Paul R Chelminski, PE Greenberg, R Colvin, R Friedman, R Melzack, R Rothman, RA Deyo, RB Lipton, RB Lipton, RC Tait, RH Fletcher, RK Portenoy, RK Portenoy, RK Portenoy, RN Jamison, RN Jamison, Robert M Malone, RS Epstein, SA Dunbar, SD Passik, SG Gelfand, SH Roth, SM Fishman, SR Savage, SR Ytterberg, Steven D Prakken, T Bodenheimer, T Bodenheimer, T Bodenheimer, Thomas M Miller, Timothy J Ives, W Arkinstall, WF Stewart, Y Olsen   +95 more
core   +4 more sources

Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis

British medical journal, 2017
Objectives To identify trends in concurrent use of a benzodiazepine and an opioid and to identify the impact of these trends on admissions to hospital and emergency room visits for opioid overdose.
E. Sun, A. Dixit, K. Humphreys, B. Darnall, L. Baker, S. Mackey   +5 more
semanticscholar   +1 more source