Commentary: Opium Alkaloids in Harvested and Thermally Processed Poppy Seeds [PDF]
Frontiers in Chemistry, 2021 Daria Kleinmeier +2 more
doaj +2 more sources
DNA methylation orchestrates secondary metabolite biosynthesis and transport in Papaver somniferum. [PDF]
PLoS ONEBackgroundPapaver somniferum (opium poppy) is a major source of benzylisoquinoline alkaloids (BIAs), including pharmaceutically important compounds such as morphine and noscapine.
Tuba Aksoylu, Mine Turktas
doaj +2 more sources
Developing benzylisoquinoline alkaloid-enriched opium poppy via CRISPR-directed genome editing: A review [PDF]
BMC Plant BiologyAmong plant-derived secondary metabolites are benzylisoquinoline alkaloids (BIAs) that play a vital role in medicine. The most conspicuous BIAs frequently found in opium poppy are morphine, codeine, thebaine, papaverine, sanguinarine, and noscapine. BIAs
Zahra Aghaali, Mohammad Reza Naghavi
doaj +2 more sources
Frontiers in Plant ScienceBenzylisoquinoline alkaloids (BIAs) produced in opium poppy have been evidenced to heal patients suffering from various diseases. They, therefore, hold an integral position in the herbal drug industry.
Zahra Aghaali +3 more
doaj +3 more sources
Concentrations of the Opium Alkaloids Morphine, Codeine, and Thebaine in Poppy Seeds are Reduced after Thermal and Washing Treatments but are Not Affected when Incorporated in a Model Baked Product. [PDF]
J Agric Food Chem, 2020 Shetge SA +4 more
europepmc +2 more sources
Update on Opium Alkaloids in Food: Exploring Their Occurrence, Effect of Culinary Processing and Advances in Analytical Methodologies. [PDF]
Compr Rev Food Sci Food SafABSTRACT Following the implementation of the new European legislation on opium alkaloids (OAs) in food in 2023, scientific research has focused on developing analytical methodologies to determine the presence of these compounds in different foods. However, health authorities continue to suggest further studies to evaluate the occurrence of main OAs and
Casado-Hidalgo G +2 more
europepmc +2 more sources
Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Int J Anal ChemHeroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M +4 more
europepmc +2 more sources
Archaeometry, EarlyView., 2022 Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares +5 more
wiley +1 more source
Nature Communications, 2022 Opium poppy accumulates alkaloids in the specialized cytoplasm of laticifers known as latex. Here the authors show that the binding of alkaloids to the abundant major latex proteins triggers quaternary structural modification that mediates a functional ...
Natali Ozber +8 more
doaj +1 more source
, 2021 Opium alkaloids, derived from crude Papaver somniferum L. plant, are potent analgesic drugs, but their use is limited because of dependence and withdrawal. Opium alkaloids activate the mesocorticolimbic dopaminergic system, which project from the ventral tegmental area to the nucleus accumbens and medial prefrontal cortex, and dopamine is critically ...
Jafarova, Demirkapu, Mahluga +1 more
openaire +3 more sources