Results 61 to 70 of about 204,956 (154)

Opium and opioid use and cancer risk: A systematic review and meta-analysis of epidemiological studies

open access: yesCancer Treatment and Research Communications
Opium use has been suggested as a possible risk factor for several cancers. While increased risk may be attributable to adulterants or smoking by-products, direct effects for opium alkaloids remains a possibility.
Kiavash Semnani   +10 more
doaj   +1 more source

Metabolome and Transcriptome Profiling of Chicory Roots Provide Insights Into Laticifer Development and Specialized Metabolism

open access: yesPhysiologia Plantarum, Volume 178, Issue 1, January/February 2026.
ABSTRACT Chicory roots produce inulin, a dietary fiber, as well as large quantities of bitter sesquiterpene lactones (STLs), which have valuable biological activities. In an effort to understand the compartmentalization of metabolism within chicory roots and the molecular basis of the development of laticifers that produce the chicory latex, we ...
Khabat Vahabi   +5 more
wiley   +1 more source

Application of Conventional and New Biotechnological Approaches for Improving of Morphinane Alkaloids Production

open access: yesJournal of Medicinal Plants, 2010
More than 12,000 alkaloids are known in plants, mostly used as medicine with a world market value of about 4 billion US$. Opium poppy, Papaver somniferum, is the most important economic source of morphinane alkaloids such as morphine, codeine, thebaine ...
E Dehghan   +3 more
doaj  

Detection of opium alkaloids in a Cypriot base-ring juglet.

open access: yesIn Analysis, 2018
A method has been developed for extracting poppy alkaloids from oily matrices, specifically lipid residues associated with archaeological ceramics. The protocol has been applied to fresh and artificially aged poppyseed oil and to residue from a Late ...
Rachel Smith   +3 more
semanticscholar   +1 more source

Exploring the Therapeutic Potential of Nobiletin in Nonsmall Cell Lung Cancer

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Nonsmall cell lung cancer (NSCLC) is one of the most prevalent cancers and leading causes of cancer‐related mortality worldwide. Despite advancements in medical treatment, current therapeutic strategies are often hindered by late‐stage diagnosis, high recurrence rates and resistance to therapies.
Adam Haysom-McDowell   +12 more
wiley   +1 more source

Fast and selective HPLC-DAD method for determination of pholcodine and related substances

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2011
Quality control of pharmaceuticals requires development of fast, efficient and reliable methods for determination of active compounds as well as known and very often unknown impurities within defined concentration ranges. In this work, a simple and rapid
Ana Petkovska   +2 more
doaj   +1 more source

Oxycodone: A Pain‐Relieving Agent With Cardioprotective Properties Against Myocardial Ischemia–Reperfusion Injury

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
In the realm of cardiovascular diseases, myocardial ischemia–reperfusion injury (MIRI) is known as one of the main life‐threatening conditions with significant morbidity and mortality. Although some therapeutic approaches, like pharmacological treatments and ischemic preconditioning, have been suggested for MIRI, offering a functional approach with ...
Mehdi Dehghani Firoozabadi   +3 more
wiley   +1 more source

Developing benzylisoquinoline alkaloid-enriched opium poppy via CRISPR-directed genome editing: A review

open access: yesBMC Plant Biology
Among plant-derived secondary metabolites are benzylisoquinoline alkaloids (BIAs) that play a vital role in medicine. The most conspicuous BIAs frequently found in opium poppy are morphine, codeine, thebaine, papaverine, sanguinarine, and noscapine. BIAs
Zahra Aghaali, Mohammad Reza Naghavi
doaj   +1 more source

Cobalamin‐Dependent Aryl Methyl Ether O‐Demethylases: Promising Enzymes for Biocatalytic Applications from Lignin Valorization to Organic Synthesis

open access: yesChemCatChem, Volume 17, Issue 21, November 10, 2025.
Cobalamin‐dependent aryl methyl ether O‐demethylases have high potential for biocatalytic applications, including lignin valorization and synthetic chemistry. In this review, we provide a detailed overview of such O‐demethylase systems identified to date from various microorganisms, including their mechanism, substrate scope and selectivity, and ...
Niels Krabbe Johnsen   +4 more
wiley   +1 more source

Molecular docking study of Papaver alkaloids to some alkaloid receptors [PDF]

open access: yesResearch Journal of Pharmacognosy, 2017
Background and objectives: More than 40 different alkaloids have been obtained from opium the most important of which are morphine, codeine, papaverine, noscapine and tabaine.
A. Nofallah   +3 more
doaj  

Home - About - Disclaimer - Privacy