Results 71 to 80 of about 199,014 (221)
Polypharmacy's Association With Mortality: Confounding From Underlying Morbidity
Journal of the American Geriatrics Society, Volume 73, Issue 8, Page 2485-2493, August 2025.ABSTRACT Background Studies consistently associate use of multiple medications with increased mortality. However, such studies often lack adequate adjustment for confounding, particularly from underlying diseases. Objective To illustrate challenges in studying the association between polypharmacy and mortality by examining this relationship in two ...
Emma Bjørk +5 more
wiley +1 more source
Fast and selective HPLC-DAD method for determination of pholcodine and related substances
Macedonian Journal of Chemistry and Chemical Engineering, 2011 Quality control of pharmaceuticals requires development of fast, efficient and reliable methods for determination of active compounds as well as known and very often unknown impurities within defined concentration ranges. In this work, a simple and rapid
Ana Petkovska +2 more
doaj +1 more source
Opium alkaloids in Papaver somniferum
, 2010 katedra: KCH; rozsah: 83The bachelor thesis deals with opium alkaloids in Papaver somniferum. It describes their chemical structure, effects and use. The aim is to analyze opium alkaloids using by thin-layer chromatography and infrared spectrophotometry ...
Stránská, Adéla
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Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis
ChemistryEurope, Volume 3, Issue 4, July 14, 2025.This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley +1 more source
Molecular docking study of Papaver alkaloids to some alkaloid receptors [PDF]
Research Journal of Pharmacognosy, 2017 Background and objectives: More than 40 different alkaloids have been obtained from opium the most important of which are morphine, codeine, papaverine, noscapine and tabaine.
A. Nofallah +3 more
doaj
Transcriptome Profiling of Alkaloid Biosynthesis in Elicitor Induced Opium Poppy
, 2015 Alkaloids are derived mainly from amino acids, and their biosynthesis includes multistep reactions. Benzylisoquinoline alkaloids (BIA), which are secondary metabolites, are produced by the medically and economically important opium poppy (Papaver ...
Gurkok, Tugba +3 more
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British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1947-1956, July 2025.Abstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Saad Hanif Abbasi +4 more
wiley +1 more source
BMC Plant BiologyAmong plant-derived secondary metabolites are benzylisoquinoline alkaloids (BIAs) that play a vital role in medicine. The most conspicuous BIAs frequently found in opium poppy are morphine, codeine, thebaine, papaverine, sanguinarine, and noscapine. BIAs
Zahra Aghaali, Mohammad Reza Naghavi
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Opium poppy as a natural source of opium alkaloids
, 2018 Cieľom tejto bakalárskej práce bolo štúdium ópiových alkaloidov obsiahnutých v maku siatom (Papaver somniferum). Práca je zameraná na ich chemické a fyzikálne vlastnosti, biosyntézu či metabolizmus.
Gállová, Michaela
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Food Science &Nutrition, Volume 13, Issue 7, July 2025.This study highlights the significant therapeutic effects of C. comosum extract in counteracting PGB‐induced toxicity in the liver, kidneys, and testes. Furthermore, in silico analysis offered insights into the protective molecular mechanisms of C. comosum phytochemicals against PGB‐induced toxicity.
Smail Mehda +11 more
wiley +1 more source