Results 71 to 80 of about 28,309 (210)

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Determination of polyphenols in Chinese jujube using ultra-performance liquid chromatography–mass spectrometry

Open Chemistry, 2023
The polyphenolic composition of the same variety of winter jujube was determined using ultra-performance liquid chromatography–mass spectrometry (UPLC–MS/MS). A metabolomic approach was employed to determine polyphenols at different developmental stages (
Liu Hongxia, Guo Xiaohua, Wu Jingjie, Liu Hui, Deng Benliang, Zhao Xusheng   +5 more
doaj   +1 more source

Metabolite Fingerprinting Using ¹H-NMR Spectroscopy and Chemometrics for Classification of Three Curcuma Species from Different Origins

Molecules, 2021
Curcuma longa, Curcuma xanthorrhiza, and Curcuma manga have been widely used for herbal or traditional medicine purposes. It was reported that turmeric plants provided several biological activities such as antioxidant, anti-inflammatory, hepatoprotector,
Laela Hayu Nurani, Abdul Rohman, Anjar Windarsih, Any Guntarti, Florentinus Dika Octa Riswanto, Endang Lukitaningsih, Nurrulhidayah Ahmad Fadzillah, Mohamad Rafi   +7 more
doaj   +1 more source

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients [PDF]

, 2015
There is a clinical need for reliable biomarkers for lung cancer that permit early diagnosis of the disease and provide prediction of histological phenotype.
AG Serrano, AM Fiorenza, Andrew W. Fogarty, CH Oak, D Kong, David A. Barrett, David R. Baldwin, E Wojcik, GL May, H Ulmer, H Yang, Helen L. Barr, J Castro de, J Chee, J Dong, J Liu, JM Poczobutt, K Yanagisawa, K Yang, L Cheng, M Haag, M Hassanein, M Hassanein, M Murphy, MJ Wakelam, MR Wenk, P Brites, R Angelis de, RA Murphy, RA Murphy, RE Smith, RL Keith, RT Sreseli, S Cedres, Srinivasarao Ravipati, WJ Scott, X Gao, X Zeng, Y Guo, YY Tyurina, ZA Fernandis   +40 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Metabolomics-guided isolation of anti-trypanosomal metabolites from the endophytic fungus Lasiodiplodia theobromae [PDF]

, 2016
Fungal endophytes offer diverse and unique secondary metabolites, making these organisms potential sources of promising drug leads. The application of high-resolution-liquid chromatography mass spectrometry and nuclear magnetic resonance-based ...
Clements, Carol J., Edrada-Ebel, RuAngelie, Kamal, Nurkhalida, Viegelmann, Christina V.   +3 more
core   +1 more source

Long‐Tea‐CLIP: An Expert‐Level Multimodal AI Framework for Fine‐Grained Green Tea Grading Across Five Sensory Dimensions

Advanced Science, EarlyView.
Long‐Tea‐CLIP (Contrastive Language‐Image Pre‐training) presents a multimodal AI framework that integrates visual, metabolomic, and sensory knowledge to grade green tea across appearance, soup color, aroma, taste, and infused leaf. By combining expert‐guided modeling with CLIP‐supervised learning, the system delivers fine‐grained quality evaluation and
Yanqun Xu, Zhengfang Xue, Qing Luo, Xu Liu, Yongquan Xu, Jing Huang, Xingcai Zhang, Xinyuan Zhang, Zhonghua Liu, Zisheng Luo   +9 more
wiley   +1 more source

Characterization of volatile flavor compounds of cigar with different aging conditions by headspace–gas chromatography–ion mobility spectrometry

Open Chemistry
Aging conditions, including time, temperature, humidity, and flipping frequency, play an important role in the flavor development of cigars. In this study, the headspace–gas chromatography–ion mobility spectrometry (HS–GC–IMS) method was used to analyze ...
Zhu Beibei, Chen Jiaowen, Song Guangfu, Jia Yun, Hu Wanrong, An Hongyue, Zhang Rongya, Ma Zhiqiang, Li Dongliang, Xue Fang   +9 more
doaj   +1 more source

Detection of Garlic Powder Adulteration Using FTIR Spectroscopy and Chemometrics: A Case Study in an Indonesia Marketplace

Journal of Food and Pharmaceutical Sciences
Garlic is a plant with numerous benefits, including its use as a culinary ingredient and for medicinal purposes. However, the rising demand does not align with the availability of garlic in Indonesia, resulting in high garlic prices.
Avika Rizky Elvira , Anggita Rosiana Putri, Luthfi Ahmad Muchlashi   +2 more
doaj   +1 more source

Quality evaluation of Cabernet Sauvignon wines in different vintages by 1H nuclear magnetic resonance-based metabolomics

Open Chemistry, 2021
A proton nuclear magnetic resonance (NMR)-based metabolomic study was used to characterize 2009, 2010, 2011, and 2012 vintages of Cabernet Sauvignon wines from Ningxia, which were vinified using the same fermentation technique.
Xu Shaochen, Zhu Jiangyu, Zhao Qi, Gao Jin, Zhang Huining, Hu Boran   +5 more
doaj   +1 more source