Results 81 to 90 of about 28,309 (210)

Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin [PDF]

, 2016
This study was aimed at examining the variations in the metabolite constituents of the different Ajwa grades and farm origins. It is also targeted at establishing the correlations between the metabolite contents and the grades and further to the nitric ...
Abas, Faridah, Abdul Hamid, Nur Ashikin, Ismail, Intan Safinar, Lajis, Nordin, Maulidiani, M., Mediani, Ahmed, Shaari, Khozirah   +6 more
core   +2 more sources

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Revealing the Effect of Different Sterilization Methods on the Quality of 'Hong yang' Kiwifruit Juice Based on OPLS-DA

Shipin gongye ke-ji
To investigate the effects of different sterilization methods on the quality of kiwifruit juice. In this study, 'Hong yang' kiwifruit was used as raw material, and significance analysis and orthogonal projections to latent structures discriminant ...
Zhe HE, Ke LI, Cuiping PAN, Huaiyu YUAN, Yuhan YANG, Kehan LI, Fei YANG, Ying LIU, Yiyue WANG, Huajia LI, Qinqin MA   +10 more
doaj   +1 more source

Non-destructive characterisation of mesenchymal stem cell differentiation using LC-MS-based metabolite footprinting [PDF]

, 2016
Bone regeneration is a complex biological process where major cellular changes take place to support the osteogenic differentiation of mesenchymal bone progenitors.
Fisk, Ian D., Kim, Dong-Hyun, Linforth, Rob S.T., Sottile, Virginie, Surrati, Amal   +4 more
core   +2 more sources

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Urinary proteome profiles associated with cognitive decline in community elderly residents—A pilot study

Frontiers in Neurology, 2023
Non-invasive and simple methods enabling easy identification of individuals at high risk of cognitive decline are needed as preventive measures against dementia.
Yumi Watanabe, Yoshitoshi Hirao, Kensaku Kasuga, Kaori Kitamura, Kazutoshi Nakamura, Tadashi Yamamoto   +5 more
doaj   +1 more source

Toward understanding myometrial regulation : metabolomic investigation reveals new pathways of oxytocin and ritodrine activity on the myometrium [PDF]

, 2016
In recent times, additional pathways involved in the regulation of the myometrium have been suggested. This also holds true for the effect of drugs such as oxytocin (OT) and β-adrenergic agonists on the myometrium.
Bafor, Enitome E., Edrada-Ebel, RuAngelie, Rowan, Edward G.   +2 more
core   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

A real time metabolomic profiling approach to detecting fish fraud using rapid evaporative ionisation mass spectrometry [PDF]

, 2017
Introduction Fish fraud detection is mainly carried out using a genomic profiling approach requiring long and complex sample preparations and assay running times.
Acutis, Pier L., Balog, Julia, Black, Connor, Chevallier, Olivier P., Elliott, Christopher T., Haughey, Simon A., Martucci, Francesca, Morris, Mike, Nikolopoulos, Dimitrios S., Pringle, Steven D., Riina, Maria V., Stead, Sara, Takats, Zoltan   +12 more
core   +1 more source

A Short Review Based on the Article Entitled “Establishment of Male and Female Eucommia Fingerprints by UPLC Combined with OPLS-DA Model and Its Application”

Journal of Alternative, Complementary & Integrative Medicine, 2023
This also demonstrates that this quantitative method for the identification of male and female E. ulmoides can provide a reference for quality control and chemical composition studies of male and female E ...
Luping Qin, Xiongyu Meng
openaire   +1 more source