Results 101 to 110 of about 41,014 (318)

Geographical discrimination of dried chili peppers using femtosecond laser ablation-inductively coupled plasma-mass spectrometry (fsLA-ICP-MS)

open access: yesCurrent Research in Food Science, 2023
This study presents a method for discriminating the geographical origin of dried chili peppers using femtosecond laser ablation-inductively coupled plasma-mass spectrometry (fsLA-ICP-MS) and multivariate analysis, such as orthogonal partial least squares
Suel Hye Hur   +6 more
doaj  

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li   +16 more
wiley   +1 more source

PCA as a Practical Indicator of OPLS-DA Model Reliability

open access: yesCurrent Metabolomics, 2016
Principal Component Analysis (PCA) and Orthogonal Projections to Latent Structures Discriminant Analysis (OPLS-DA) are powerful statistical modeling tools that provide insights into separations between experimental groups based on high-dimensional spectral measurements from NMR, MS or other analytical instrumentation.
Worley, Bradley, Powers, Robert
openaire   +3 more sources

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye   +13 more
wiley   +1 more source

Novel Zwitterionic Polyurethane‐in‐Salt Electrolytes with High Ion Conductivity, Elasticity, and Adhesion for High‐Performance Solid‐State Lithium Metal Batteries

open access: yesAdvanced Energy Materials, EarlyView.
A novel zwitterionic polyurethane‐in‐salt electrolyte (zPU‐SPE) is developed, achieving high ionic conductivity (3.7 × 10⁻⁴ S cm−1 at 25 °C), superior adhesion to lithium metal, and exceptional elasticity. This innovative electrolyte enables stable solid‐state lithium metal batteries, demonstrating excellent cycling stability, strong interfacial ...
Kun Wang   +15 more
wiley   +1 more source

Evaluating the physiological and biochemical responses of melon plants to NaCl salinity stress using supervised and unsupervised statistical analysis

open access: yesPlant Stress, 2022
Salinity is a major environmental issue affecting plant production, particularly in the Middle East. Multivariate data analysis including principal component analysis (PCA), hierarchical clustering analysis (HCA), and orthogonal projections to latent ...
Behrooz Sarabi, Jaleh Ghashghaie
doaj  

Protein mechanical unfolding: importance of non-native interactions

open access: yes, 2009
Mechanical unfolding of the fourth domain of Distyostelium discoideum filamin (DDFLN4) was studied by all-atom molecular dynamics simulations, using the GROMOS96 force field 43a1 and the simple point charge explicit water solvent.
Berendsen H. J. C.   +4 more
core   +1 more source

LiNO3‐Based Electrolyte with Fast Kinetics for Lithium Metal Batteries Under Practical Conditions

open access: yesAdvanced Energy Materials, EarlyView.
A LiNO3‐based electrolyte enables lithium metal batteries to achieve exceptional cycling stability (430 cycles) and ultrafast kinetics (2.35 mAh cm−2 at 12 mA cm−2) under practical conditions. The electrolyte's unique solvation structure and Li2O‐Li3N‐rich interphase facilitate rapid ion transport, outperforming costly LiFSI‐based systems and paving ...
Pengcheng Li   +4 more
wiley   +1 more source

Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via ERG + VEP

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li   +9 more
wiley   +1 more source

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