Results 131 to 140 of about 41,014 (318)

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

open access: yesChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone   +17 more
wiley   +1 more source

OPL volume 1298 Cover and Front matter [PDF]

open access: bronze, 2011
Auriane Cunningham   +68 more
openalex   +1 more source

Solvation Structure and Dynamics of the Thiocyanate Anion in mixed N,N‐Dimethylformamide‐Water Solvents: A Molecular Dynamics Approach

open access: yesChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The solvation structure and dynamics of the SCN− anion in mixed N, N‐Dimethylformamide (DMF)‐water liquid solvents is investigated using classical molecular dynamics simulations. A preferential solvation of SCN− by the water molecules is observed in the first hydration shell, followed by a second shell consisting by both DMF and water molecules.
Ioannis Skarmoutsos, Ilias G. Karvounis
wiley   +1 more source

Coconut Testa Flour Sub-Fractions: Correlation Between FTIR Spectral Data and α-Glucosidase Inhibitory Activities

open access: yesFoods
Fourier-transform infrared spectroscopy (FTIR) serves as a rapid analytical technique to characterize food specimens chemically. The purpose of this study was to investigate the potential of FTIR combined with multivariate statistics to detect Alpha ...
Rasika Gunarathne   +4 more
doaj   +1 more source

OPL volume 1322 Cover and Front matter [PDF]

open access: bronze, 2011
Rudi Santbergen   +6 more
openalex   +1 more source

Bombyx Mori Silk Fibroin as Sustainable Organocatalyst for Diastereoselective Michael Additions

open access: yesChemSusChem, Accepted Article.
Powdered silk fibroin (PSF) extracted from Bombyx mori cocoons is reported as a heterogeneous organocatalyst in the selective Michael 1,4 addition of nitromethane to α,β‐unsaturated carbonyl compounds, affording Michael adducts in almost quantitative yields, with complete anti diastereoselectivity and in mild conditions.
Carola Ricciardelli   +8 more
wiley   +1 more source

OPL volume 1408 Cover and Front matter [PDF]

open access: bronze, 2012
Houssem Kallel   +51 more
openalex   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

OPL volume 1406 Cover and Front matter [PDF]

open access: bronze, 2012
Miriam P. Trubelja   +9 more
openalex   +1 more source

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

open access: yesExploration, EarlyView.
This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...
Zhen‐feng He   +16 more
wiley   +1 more source

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