Results 131 to 140 of about 41,014 (318)
Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization
ChemMedChem, EarlyView.ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...Gerardina Smaldone, Maria Rosaria Miranda, Francesca Di Matteo, Valeria Napolitano, Michela Aliberti, Simona Musella, Veronica Di Sarno, Gianluigi Lauro, Giuseppe Bifulco, Giacomo Pepe, Giovanna Aquino, Mario Felice Tecce, Isabel Maria Gomez‐Monterrey, Pietro Campiglia, Carmine Ostacolo, Alessia Bertamino, Vincenzo Vestuto, Tania Ciaglia +17 morewiley +1 more sourceOPL volume 1298 Cover and Front matter [PDF]
, 2011 Auriane Cunningham, Gilbert Étienne, Ceri A. Williams, Paulina Unifantowicz, Zbigniew Oksiuta, N. Baluc, George Smith, Emmanuelle A. Marquis, Hiroshi Oka, Yosuke Yamazaki, Hiroshi Kinoshita, Naoyuki Hashimoto, Somei Ohnuki, Junpei Nakayama, Kiyoshi Kiuchi, Yukio Nakahara, Chiaki Kato, Masahiro Yamamoto, Takashi Tsukada, Atsushi Watanabe, Motomasa FUSE, Tohru Sugahara, Ken Kurosaki, Aikebaier Yusufu, Hiroaki Muta, Hui Niu, Huiyang Gou, Rodney C. Ewing, Jie Lian, R.C. Ko, Y Miro, E Serruys, H Bordas, Shingo Kanehira, Chiwon Moon, Eita Tochigi, Naoya Shibata, Yuichi Ikuhara, Martin Gilbert, Carine Davoisne, Martin C. Stennett, Neil C. Hyatt, Nianhua Peng, C. Jeynes, William Lee, Eliana Kamin ́ska, Iwona Pasternak, Michał A. Borysiewicz, M. Guziewicz, Anna Piotrowska, Elz ̇bieta Dynowska, R. Jakieła, Valery Kolkovski, Marie‐Antoinette di Forte‐Poisson, Piyush Jaiswal, Abdul Sathar, Arshiyan Shariff, Mohammed Saif, Sukanya Dhar, S Shivashankar, Gyudo Lee, Kihwan Nam, Suho Jeong, Huihun Jung, Bumjoon Choi, Sang Kil Lee, Dae Young Yoon, Kilho Eom, Taeyun Kwon +68 moreopenalex +1 more sourceBombyx Mori Silk Fibroin as Sustainable Organocatalyst for Diastereoselective Michael Additions
ChemSusChem, Accepted Article.Powdered silk fibroin (PSF) extracted from Bombyx mori cocoons is reported as a heterogeneous organocatalyst in the selective Michael 1,4 addition of nitromethane to α,β‐unsaturated carbonyl compounds, affording Michael adducts in almost quantitative yields, with complete anti diastereoselectivity and in mild conditions.Carola Ricciardelli, Giorgio Rizzo, Pietro Cotugno, Antonio Salomone, Daniela Trisciuzzi, Orazio Nicolotti, Erica Colaprico, Cosimo Damiano Altomare, Gianluca Maria Farinola +8 morewiley +1 more sourceOPL volume 1408 Cover and Front matter [PDF]
, 2012 Houssem Kallel, A. Chehaidar, Arnaud Arbouet, T. Baron, A. Potié, B. Salem, Vincent Paillard, Mohammad Montazeri, Aaron Wade, Melodie A. Fickenscher, Howard Jackson, Leigh M. Smith, J.M. Yarrison-Rice, Qiang Gao, Hsih Yin Tan, C. Jagadish, Apurba Dev, Kristian Frank, Andreas Rosenauer, T. Voss, Daniel Schmidt, Chad Briley, E. F. Schubert, M. Schubert, T. Stoïca, Anna Haab, David Griesche, M. Mikulics, F. Limbach, Timo Schumann, Tobias Gotschke, Eli Sutter, Raffaella Calarco, H. Hardtdegen, Detlev Gru, A Herna ́ndez-Mı ́nguez, Mu ̈ller, C Pfu, Steffen Breuer, O. Brandt, Moura Lima, A Garcı ́a-Cristo, A. Cantarero, Lutz Geelhaar, H. Riechert, P. V. Santos, Jean‐Christophe Harmand, Frank Glas, G. Patriarche, Fauzia Jabeen, Mohamed Re, ́da Ramdani +51 moreopenalex +1 more sourceDevelopment of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research
Environmental Toxicology and Chemistry, EarlyView.Abstract
There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann +9 morewiley +1 more sourceOPL volume 1406 Cover and Front matter [PDF]
, 2012 Miriam P. Trubelja, D.I. Potter, Claudia J. Rawn, Karren L. More, J.J. Helble, A Wilson, Samuel Mishra, Beena Rai, Radhey S. Gupta, Kunal Ghosh +9 moreopenalex +1 more sourceSputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study
Exploration, EarlyView.This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...Zhen‐feng He, Xiao‐xian Zhang, Cui‐xia Pan, Xin‐zhu Yi, Yan Huang, Chun‐lan Chen, Shan‐shan Zha, Lai‐jian Cen, Han‐qin Cai, Lei Yang, Jia‐qi Gao, Hui‐min Li, Zhen‐hong Lin, Sheng‐zhu Lin, Zhang Wang, Nan‐shan Zhong, Wei‐jie Guan +16 morewiley +1 more source