Results 171 to 180 of about 28,317 (243)

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen   +16 more
wiley   +1 more source

Advancing Raman Calibration: Automated Data Generation, Monitoring, and Control in Multi‐Parallel Perfusion Mini Bioreactors

open access: yesBiotechnology Journal, Volume 21, Issue 3, March 2026.
Graphical Abstract and Lay Summary The biopharmaceutical industry is enhancing production efficiency and affordability through process intensification techniques like perfusion, requiring advanced process analytical technologies (PAT) for real‐time monitoring.
Rafael Machleid   +5 more
wiley   +1 more source

Application of untargeted plasma metabolomics and machine learning to construct a diagnostic model for hypertrophic cardiomyopathy: a case-control study. [PDF]

open access: yesMetabolomics
Li R   +14 more
europepmc   +1 more source

Organic Electrolyte Composed of Strongly and Weakly Coordinating Molecules for Sodium‐Ion Battery. A Molecular Dynamics Simulation Study

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 2, March 2026.
Molecular dynamics simulations reveal that the addition of weakly coordinating solvents disrupts stable Na+ solvation with various coordinating configurations, accelerating solvents exchange and promoting Na+ migration. The optimized electrolyte achieves the highest ionic conductivity as well as the fractional ionic conductivity of Na+ of 3.68 ± 0.36 ...
Hongjin Li   +6 more
wiley   +1 more source

Comparative Analysis of Fungal Communities and the Key “Golden‐Flower” Fungi in Fu Brick Tea From Seven Chinese Regions and Their Effects on the Quality of Summer‐Autumn Tea

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
This study systematically investigated 52 Fu brick tea (FBT) samples collected from seven representative regions in China. High‐through put sequencing revealed that Aspergillus, Wallemia, and Candida were the predominant fungal genera across the samples.
Lisha Ran   +9 more
wiley   +1 more source

Serum metabolomics coupled with HR-VWI radiomics reveals metabolic alterations in asymptomatic carotid artery stenosis. [PDF]

open access: yesJ Cereb Blood Flow Metab
Fan Y   +9 more
europepmc   +1 more source

Protective Effects of Auricularia auricula Polysaccharides on Acute Lung Injury by Regulating Intestinal Flora and Metabolism

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu   +8 more
wiley   +1 more source

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