Results 191 to 200 of about 41,014 (318)

Steroidomic Changes in the Cerebrospinal Fluid of Women with Multiple Sclerosis. [PDF]

Int J Mol Sci
Kancheva R, Kubala Havrdová E, Velíková M, Kancheva L, Včelák J, Ampapa R, Židó M, Štětkářová I, Škodová T, Hill M.   +9 more
europepmc   +1 more source

Orthogonal partial least-squares discriminant analysis (OPLS-DA) score and coefficient loading plots derived from the 1H NMR spectra derived from plasma at 4 weeks (A, C) or 8 weeks (B, D) after 5/6 nephrectomy and sham operation.

, 2014
Kim Ju-Ae, Choi Hyo-Jung, Yong‐Kook Kwon, Ryu Do Hyun, Kwon Tae-Hwan, Hwang Geum-Sook   +5 more
openalex   +1 more source

Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus)

Integrative Zoology, EarlyView.
The gut microbiota regulates lipid metabolism of Gansu zokor (Eospalax cansus) through the bile acid pathway in hypoxic environments, reflecting the unique survival strategy of subterranean rodents to maintain lipid metabolism homeostasis and flexible energy metabolism in hypoxic environments.
Maohong Yang, Yingying Zhang, Zhuohang Li, Tianyi Liu, Jianping He, Jingang Li   +5 more
wiley   +1 more source

Transferability of Data Sets between Machine-Learned Interatomic Potential Algorithms. [PDF]

J Chem Theory Comput
Niblett SP, Kourtis P, Magdău IB, Grey CP, Csányi G.   +4 more
europepmc   +1 more source

Age‐Related Complement C3 Drives Memory Impairments and Associated Neuropathologies in a Mouse Model

Aging Cell, EarlyView.
Age‐related complement C3 elevation induces memory impairments and neuropathology by dysregulating astrocytic insulin signaling and triggering mitochondrial dysfunction. Critically, antibody blockade of C3 in mouse brain tissue effectively reversed learning and memory deficits in mice, demonstrating that targeting C3 is a promising therapeutic strategy.
Miaomiao Du, Yujia Wang, Xinyuan Wang, Yifei Liu, Fuchuan Xiao, Jing Zhang, Xia Meng, Kunhe Ma, Na Wu, Baian Chen, Jing Lu   +10 more
wiley   +1 more source

Metabolic pathways in anal fistula: paving the way for innovative treatments. [PDF]

Am J Transl Res
Wang M, Pan Y, Zhang X, Pan C, Cao Y.
europepmc   +1 more source

Topologies, structures and parameter files for lipid simulations in GROMACS with the OPLS-aa force field: DPPC, POPC, DOPC, PEPC, and cholesterol

, 2015
Waldemar Kulig, Marta Pasenkiewicz‐Gierula, Tomasz Róg   +2 more
openalex   +1 more source

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

Cell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi, Hengjie Wang, Shuai Zhu, Minjian Chen, Xuejiang Guo, Qiang Wang, Ling Gu   +6 more
wiley   +1 more source

A randomized controlled cross-over trial of differences in acute effects on serum metabolites from isocaloric meals based on red meat, fatty fish, or soy protein. [PDF]

Eur J Nutr
Lindqvist HM, Hulander E, Bärebring L, Gjertsson I, Winkvist A.   +4 more
europepmc   +1 more source

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

Cell Proliferation, EarlyView.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu, Xuehan Zhao, Ying Fang, Cong Wang, Yichang Tian, Wan Tu, Qiqian Wu, Long Yan, Xiaokui Yang   +8 more
wiley   +1 more source