Results 31 to 40 of about 30,316 (263)

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Evaluating the physiological and biochemical responses of melon plants to NaCl salinity stress using supervised and unsupervised statistical analysis

Plant Stress, 2022
Salinity is a major environmental issue affecting plant production, particularly in the Middle East. Multivariate data analysis including principal component analysis (PCA), hierarchical clustering analysis (HCA), and orthogonal projections to latent ...
Behrooz Sarabi, Jaleh Ghashghaie
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Prediction of Antimicrobial and Antioxidant Activities of Mexican Propolis by 1H-NMR Spectroscopy and Chemometrics Data Analysis

Molecules, 2017
A feasibility study to predict antimicrobial and antioxidant activity properties of propolis extracts using 700-MHz 1H-NMR spectra and multivariate regression data analysis is presented.
J. Fausto Rivero-Cruz, Eduardo Rodríguez de San Miguel, Sergio Robles-Obregón, Circe C. Hernández-Espino, Blanca E. Rivero-Cruz, José Pedraza-Chaverri, Nuria Esturau-Escofet   +6 more
doaj   +1 more source

Evaluation of Internet-based pharmaceutical care effect on young and middle-aged patients with hypertension by the principal component analysis and the Markov cohort during COVID-19 pandemic

Health and Quality of Life Outcomes, 2023
Background Pharmaceutical care has the potential to improve hypertension control rates in young and middle-aged patients. Due the COVID-19 epidemic, standard intervention methods may not be applicable.
Xinmei Li, Wenxiu Xu, Xiaofeng Mo, Fan Wu, Minghong Qu, Junxian Ye, Wenxing Wu, Haizhi Li, Te Li   +8 more
doaj   +1 more source

Angstrom‐Scale Confined Ion Sieve and Accelerator for Efficient Aqueous Zinc Batteries

Advanced Materials, EarlyView.
An angstrom‐scale confined ion accelerator strategy is proposed for ultra‐stable aqueous Zn anodes. Selective and precise transport of hydrated Zn(H2O)62+, Zn2+ cations, H2O molecules, and SO42− anions is achieved by in‐plane atomic Ti vacancies and angstrom‐scale interlayer free spacing within the Ti0.87O2 interfacial layer, leading to homogeneous Zn ...
Xing Peng, Caichao Ye, Yingqiang Li, Zhihang Liu, Kunxi Luan, Jinbo Fan, Honglan Huang, Chao Liu, Na Shen, Zhen Hou, Wenyao Zhang, Yongsheng Fu, Mingzhe Chen, Linfeng Hu, Pan Xiong, Guoxiu Wang, Junwu Zhu   +16 more
wiley   +1 more source

OPL Script: Composing and Controlling Models [PDF]

, 2000
This paper is a brief introduction to OPLScript, a script language for composing and controlling optimization models. OPLScript makes it possible to state concisely many applications that require solving several instances of the same model (e.g., to perform some sensivity analysis), a sequence of models, or a combination of both as in column-generation
Pascal Van Hentenryck, Laurent Michel
openaire   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Structural, Microstructural, Elastic, and Microplastic Properties of Aluminum Wires (from AAAC (A50) Cables) after Fatigue Tests

Metals, 2023
Single Al wires from unused AAAC (A50) cables were studied after laboratory fatigue testing, which simulated processes arising in these wires during their operation in the cables of overhead power lines (OPLs) and are valuable for predicting the lifespan
Aleksandr A. Levin, Maria V. Narykova, Alexey I. Lihachev, Boris K. Kardashev, Andrej G. Kadomtsev, Andrei G. Panfilov, Nikita D. Prasolov, Roman V. Sokolov, Pavel N. Brunkov, Makhsud M. Sultanov, Alexander V. Strizhichenko, Ilia A. Boldyrev   +11 more
doaj   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source