Results 51 to 60 of about 38,044 (266)

Evaluation of Internet-based pharmaceutical care effect on young and middle-aged patients with hypertension by the principal component analysis and the Markov cohort during COVID-19 pandemic

Health and Quality of Life Outcomes, 2023
Background Pharmaceutical care has the potential to improve hypertension control rates in young and middle-aged patients. Due the COVID-19 epidemic, standard intervention methods may not be applicable.
Xinmei Li, Wenxiu Xu, Xiaofeng Mo, Fan Wu, Minghong Qu, Junxian Ye, Wenxing Wu, Haizhi Li, Te Li   +8 more
doaj   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

OPLS-DA of liver metabolites obtained from cultured and wild female eels.

, 2019
(A) water phase fraction and (B) organic phase fraction. S-plot generated from OPLS-DA of (C) water phase fraction and (D) organic phase fraction.
Miyuki Mekuchi (2503714), Takeshi Hano (2505832), Masato Higuchi (6686000), Hitoshi Imaizumi (4818915)   +3 more
core   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Osteopenia-osteoporosis discrimination in postmenopausal women by 1H NMR-based metabonomics.

PLoS ONE, 2019
This is a report on how 1H NMR-based metabonomics was employed to discriminate osteopenia from osteoporosis in postmenopausal women, identifying the main metabolites associated to the separation between the groups. The Assays were performed using seventy-
T A Pontes, A D Barbosa, R D Silva, M R Melo-Junior, R O Silva   +4 more
doaj   +1 more source

Structural, Microstructural, Elastic, and Microplastic Properties of Aluminum Wires (from AAAC (A50) Cables) after Fatigue Tests

Metals, 2023
Single Al wires from unused AAAC (A50) cables were studied after laboratory fatigue testing, which simulated processes arising in these wires during their operation in the cables of overhead power lines (OPLs) and are valuable for predicting the lifespan
Aleksandr A. Levin, Maria V. Narykova, Alexey I. Lihachev, Boris K. Kardashev, Andrej G. Kadomtsev, Andrei G. Panfilov, Nikita D. Prasolov, Roman V. Sokolov, Pavel N. Brunkov, Makhsud M. Sultanov, Alexander V. Strizhichenko, Ilia A. Boldyrev   +11 more
doaj   +1 more source

OPLS-DA scatter plots of GC/MS data of extracts from the liver of mice.

, 2016
Orthogonal partial least-squares discriminant analysis (OPLS-DA) score plots (t(1)P/ t(2)O) of the liver of C3H group (A) and G6PDx group (B).
Guobing Zhong (3178971), Dongjing Yan (3178965), Huazong Zeng (304005), Wangwei Cai (3178968), Guankui Du (3178974), Man Xiao (556153)   +5 more
core   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

OPLS-DA score plot of melon fruits from non-grafted plants and plants grafted onto muskmelon or pumpkin rootstocks.

, 2019
(A) OPLS-DA score plot of melon fruits from non-grafted plants and from plants grafted onto pumpkin rootstocks. R2X = 0.586, R2Y = 0.955, Q2 = 0.873. (B) OPLS-DA score plot of melon fruits from plants grafted onto muskmelon rootstocks and plants grafted ...
Qiang Cui (214006), Shuangshuang Zhang (701020), Wensheng Zhao (145502), Jiahao Wang (4710915), Lanchun Nie (7485674), Yaqian Duan (6459467), Chang Ge (4280119)   +6 more
core   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source