Results 71 to 80 of about 553,104 (200)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Clinical, outcome and aetiological chacteristics of inflammatory optic neuropathies. A series of Algerian patients. [PDF]

Batna Journal of Medical Sciences
Introduction. Inflammatory optic neuropathies (ION) are frequent neuroophthalmological emergencies. They often pose an etiological problem. Objectives. To study the clinical, radiological, etiological and evolutionary particularities of ION in Algerian
Mohamed Islam KEDIHA, Dalila MOUALEK, Farida MOSTEFAOUI, Lamia ALI PACHA   +3 more
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

F2b09 Optic Disc Swelling from Malignant Optic Nerve Glioma

, 1971
Malignant optic nerve glioma of adulthood with blindness and optic disc edema. Right image shows white material extruded from the swollen optic disc. This material is myelin being squeezed into the eye from the nerve infarction.
William F. Hoyt, MD
core  

The rare case of optic nerve cavernoma: A case report depicting the diagnostic challenge

Radiology Case Reports
The manuscript describes a case of Cavernous Malformation in the optic pathway which is extremely rare, accounting for less than 1% of central nervous system cavernomas.
Rushil Sharma, MD
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Optic Neuritis Mimicking Ischemic Optic Neuropathy and Optic Glioma [PDF]

, 2014
Purpose : To report a case of optic neuritis difficult to differentiate from ischemic optic neuropathy and optic nerve glioma. Case summary : A 63-year-old male visited our clinic because of a sudden painless decrease in visual acuity in his right eye ...
홍사민, 성공제, 강은민, 김찬윤   +3 more
core   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Use of Optical Coherence Tomography to Detect Retinal Nerve Fiber Loss in Children With Optic Pathway Glioma

Frontiers in Neurology, 2018
Optic pathway glioma (OPG) presents in childhood and can cause significant morbidity and visual loss. Magnetic resonance imaging (MRI) is the current imaging modality of choice for evaluation of OPG progression, but it is a relatively limited resource ...
Alon Zahavi, Alon Zahavi, Helen Toledano, Helen Toledano, Rony Cohen, Rony Cohen, Sara Sella, Judith Luckman, Shalom Michowiz, Shalom Michowiz, Nitza Goldenberg-Cohen, Nitza Goldenberg-Cohen, Nitza Goldenberg-Cohen   +12 more
doaj   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source