Results 71 to 80 of about 1,469,459 (252)

Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang, Wanru Chen, Xiangpen Li, Hengjian Lu, Chenguang Li, Xiaoni Zhang, Lulu Bu, Xiaoyu Xu, Qingyu Shen, Ying Peng   +9 more
wiley   +1 more source

Optic Nerve Avulsion after Blunt Trauma

, 2014
Optic nerve avulsion is an uncommon presentation of ocular trauma with a poor prognosis. It can be seen as complete or partial form due to the form of trauma.
Güner Üney, Muhammed Necati Demir, Hacı Halil Karabulut   +2 more
core   +1 more source

Reactive Fibroblasts in Response to Optic Nerve Crush Injury

, 2020
Traumatic optic neuropathy leads to bidirectional degeneration of retinal ganglion cells and axons and results in optic nerve scaring, which inhibits the regeneration of damaged axons.
Wang, Ningli, Liu, Yuan, Lee, Jae K, Liu, Xiangxiang, Khodeiry, Mohamed, Lee, Richard K, Jin, Huiyi, Kong, Weizheng, Xiangxiang Liu, Yuan Liu, Weizheng Kong, Mohamed M. Khodeiry, Huiyi Jin, Richard K. Lee, Ningli Wang, Jae K. Lee   +15 more
core   +1 more source

Chorioretinitis plastica sclopetaria in gunshot injury with review of literature

Indian Journal of Ophthalmology. Case Reports
We present the case of a patient with a gunshot injury in her left eye causing traumatic chorioretinitis sclopetaria. Chorioretinitis Sclopetaria Plastica is the characteristic pattern of rupture of the choroid and overlying neurosensory retina secondary
Rajwinder Kaur, Harijot Singh, Balbir Khan, Vinita Jindal   +3 more
doaj   +1 more source

Blocking LINGO-1 in vivo reduces degeneration and enhances regeneration of the optic nerve

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2016
Background Two ongoing phase II clinical trials (RENEW and SYNERGY) have been developed to test the efficacy of anti-LINGO-1 antibodies in acute optic neuritis and relapsing forms of multiple sclerosis, respectively. Across a range of experimental models,
Melissa M Gresle, Yaou Liu, Trevor J Kilpatrick, Dennis Kemper, Qi-Zhu Wu, Bing Hu, Qing-Ling Fu, Kwok-Fai So, Guoqing Sheng, Guanrong Huang, Blake Pepinsky, Helmut Butzkueven, Sha Mi   +12 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

CX3CL1-CX3CR1 axis protects retinal ganglion cells by inhibiting microglia activation in a distal optic nerve trauma model

Inflammation and Regeneration
Background The chemokine CX3CL1 has been reported to play an important role in optic nerve protection, but the underlying mechanism is still unclear. CX3CR1, the only receptor of CX3CL1, is specifically expressed on retinal microglia, whose activation ...
Huan Yu, Bingqiao Shen, Ruiqi Han, Yang Zhang, Shushu Xu, Yumeng Zhang, Yanzhi Guo, Ping Huang, Shouyue Huang, Yisheng Zhong   +9 more
doaj   +1 more source

The content and reporting completeness of physical therapist‐led interventions for glenohumeral osteoarthritis: a systematic review

Arthritis Care &Research, Accepted Article.
Objectives This study synthesised the content and reporting completeness of published physical therapist‐led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL and PEDro (until June 2025) for any peer‐reviewed articles/studies describing ...
Daha G Muhammad, Nadine E Foster, Mickylle Pelaez, Karina O'Leary, Ilana N Ackerman, Jonathan G Quicke   +5 more
wiley   +1 more source

Self-inflicted repetitive optic nerve injury: a case report.

, 2002
PURPOSE: To describe an obsessive-compulsive patient who developed blindness after self-inflicted repetitive optic nerve injury. METHODS: Case report.
Philippart, Patrick, Boschi, Antonella, A. Luts, M. Detry-Morel, Detry-Morel, Michèle, P. Philippart, Luts, Alain, A. Boschi   +7 more
core   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source