Results 81 to 90 of about 1,469,459 (252)

Optic nerve regeneration in larval zebrafish exhibits spontaneous capacity for retinotopic but not tectum specific axon targeting.

open access: yesPLoS ONE, 2019
In contrast to mammals, retinal ganglion cells (RGC) axons of the optic nerve even in mature zebrafish exhibit a remarkable capacity for spontaneous regeneration.
Beth M Harvey   +2 more
doaj   +1 more source

Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]

open access: yes, 2012
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo   +24 more
core   +2 more sources

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

Diffuse Atrophy - Evolution of Optic Disc Palor After Optic Nerve Transection

open access: yes
Injury on December 8, 1978. Evolution of optic disc pallor after optic nerve transection. Woman having rhinoplasty suffered optic nerve transection. One day after nerve transection. Note dilated veins. Left eye. Photo taken December 9, 1978.
William F. Hoyt, MD
core   +3 more sources

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

open access: yesMediators of Inflammation, 2019
As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts   +6 more
doaj   +1 more source

Electrical Stimulation to Enhance Axonal Regeneration after Optic Nerve Injury

open access: yes, 2003
We sought to determine if electrical stimulation of the optic nerve, when performed just before an optic nerve crush injury, would enhance regeneration of retinal ganglion cell ...
Prem S. Subramanian, MD; Lawrence Schramm, MD; Paul N. Hoffman, MD
core  

Biodegradable 3D‐Printable and Coatable Antifouling Composites for Marine Applications

open access: yesAdvanced Functional Materials, EarlyView.
Marine biofouling damages submerged surfaces and raises greenhouse gas emissions. Biodegradable antifouling biocomposites were developed by hot‐mixing beeswax, Tween 80, and calcium stearate or stearic acid. Adjusting the component ratio enables processing via hot‐pressing, 3D‐printing, or dip‐coating.
Gabriele Corigliano   +17 more
wiley   +1 more source

Approach to the Diagnosis and Differentiation of Glaucomatous and Nonglaucomatous Optic Neuropathies

open access: yes, 2014
Optic neuropathy denotes degeneration of the retinal ganglion cells with functional and structural impairment of the optic nerve. Functional damage of the optic nerve can be evaluated by checking visual acuity, color vision, pupillary function, and ...
Carmen K. M. Chan   +3 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

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