Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley +1 more source
Anterior basal meningiomas: Can different approaches make a difference? [PDF]
Anmar Badran S +6 more
europepmc +1 more source
Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience
Atomically precise clusterzymes, engineered via atomic and ligand design, serve as programmable platforms for neuroscience applications. They demonstrate tailored biocatalysis for neuroinflammation, tunable optical properties for deep‐tissue bioimaging and 3D visualization, and enhanced charge transfer for brain–computer interfaces.
Si Sun +6 more
wiley +1 more source
Orbital Retinoblastoma: From Palliation to Cure by Sequential Multimodal Multidisciplinary Therapy - A Case Report. [PDF]
Ng VWW +5 more
europepmc +1 more source
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Update on anterior clinoid process removal in anterior clinoid meningioma surgery: literature review, and a new didactical concept. [PDF]
Arnautovic KI, Lasica N.
europepmc +1 more source
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen +12 more
wiley +1 more source
Spatial Proteomic Analysis Highlights Molecular Reprogramming in Optic Nerve Invasive Retinoblastoma. [PDF]
Zhu T +14 more
europepmc +1 more source
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu +12 more
wiley +1 more source
Posttraumatic intracranial migration of silicone oil after treatment of retinal detachment, a rare complication. [PDF]
Aroll A +3 more
europepmc +1 more source

