Results 121 to 130 of about 3,058,814 (268)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Current optical technologies for wireless access

, 2009
The objective of this paper is to describe recent activities and investigations on free-space optics (FSO) or optical wireless and the excellent results achieved within SatNEx an EU-framework 6th programme and IC 0802 a COST action.
Sheikh Muhammed, S., Ghassemlooy, Zabih, Javornik, Tomaz, Kandus, Gorazd, Awan, Muhammad, Brandl, P., Capsoni, Carlo, Leitgeb, Erich, Nebuloni, R.   +8 more
core  

Fixed-rate-breaking All-optical OFDM system using time-domain hybrid PAM with sparse subcarrier multiplexing and power-loading for optical short-reach transmission

, 2020
All-optical TDHP-OFDM system with four-sparse-subcarrier-multiplexing and power-loading has been proposed for data-rate-adaptive transmission. 40-Gbit/s, 60-Gbit/s, and 80-Gbit/s can be selected by changing the ratio of PAM2 and PAM4, and all BERs ...
Kodama T., Wada N., Cincotti G., Maruta A.   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Radiation pressure on a moving body: Beyond the Doppler effect

, 2012
Copyright © 2012 Optical Society of AmericaThis paper was published in Journal of the Optical Society of America B and is made available as an electronic reprint with the permission of OSA.
Artoni, M., ARTONI, Maurizio, La Rocca, G.C., G. C. La Rocca, S. A. R. Horsley, Horsley, S. A. R., Horsley, S.A.R., La Rocca, G. C.   +7 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The BOOM project: Towards 160 Gb/s packet switching using soi photonic integrated circuits and hybrid integrated optical flip-flops

, 2012
We present a 160 Gb/s optical packet switching architecture that performs label detection and packet wavelength conversion using photonic components integrated on silicon-on-insulator (SOI) waveguide boards. For label detection, we report the fabrication
Gomez-Agis, F., P. De Heyn, D. Van Thourhout, Lazarou, I., Zimmermann, L, Avramopoulos, H, H. J. S. Dorren, Dorren, HJS, Stamatiadis, C., Vyrsokinos, K., Lazarou, I, Voigt, K, Voigt, K., Dorren, H.J.S., K. Vyrsokinos, De Heyn, PeterUGent0020042433028020001859529722522864460E25F51E-F0EE-11E1-A9DE-61C894A0A6B4, Vyrsokinos, K, K. Voigt, Stampoulidis, L., Van Thourhout, DriesTW058010010572560000-0003-0111-431XF4F6F962-F0ED-11E1-A9DE-61C894A0A6B4, Van Thourhout, Dries, H. Avramopoulos, F. Gomez-Agis, I. Lazarou, Zimmermann, L., Heyn, de, P., C. Stamatiadis, L. Zimmermann, Thourhout, Van, D., Van Thourhout, D, Gomez-Agis, F, De Heyn, P, L. Stampoulidis, Stampoulidis, L, Avramopoulos, H., De Heyn, Peter, Stamatiadis, C   +36 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Recent advances in ultrafast optical parametric oscillator frequency combs

, 2014
We discuss recent advances in the stabilization and application of femtosecond frequency combs based on optical parametric oscillators (OPOs) pumped by femtosecond lasers at 800 and 1060 nm.
Reid, Derryck T.; id_orcid, McCracken, Richard A.; id_orcid, Zhang, Zhaowei   +2 more
core   +1 more source